Brede meta-analysis


DTU Informatics >>> Neuroinformatics > Services > Brede meta-analysis

Input

Brede Wiki CSV title: 


Column names Number Mean SD Events
Experimentals:
Controls:

Go to: Article | Data | CSV

Original data

TitleFirst AuthorYearLink to paperBipolars numberControls, number ofDiagnosisMethodCT basedAge Bipolarssd age bp ttxSD Age Bipolarsage cntrl ttxAge ControlsSD Age ControlsFemale BPsFemale CtrlsBipolars numbers included in meta-analysisControls, numbers included in meta-analysisBipolar (left)Bipolar SD (left)Control (left)Control SD (left)Bipolar (right)Bipolar SD (right)Controls (right)Controls SD (right)BipolarsBipolars SDControlsControls SD
Structural brain abnormalities in first-episode maniaStrakowski SM (B)1993http://dx.doi.org/10.1016/0006-3223(93)90098-X1716DSM-III-RMRI028.46.830.97.310917165.90.95.50.7
Aylward EH (Females)1994http://ajp.psychiatryonline.org/cgi/reprint/151/5/6871413DSM-III-RMRI040.710.438.89.2141314134042.7987.64375974.3
Aylward EH (Males)1994http://ajp.psychiatryonline.org/cgi/reprint/151/5/6871617DSM-III-RMRI037.911.936.790016174625.41008.53780.7916.2
Dupont RM (A)1995See Sept 1995 p747, Archives of General Psychiatry3626DSM-III-RMRI036.610.839.19.4121136261808.81259.721806.35243.73
Sax KW1999Jan 1999 p139 American Journal of Psychiatry (OVID)1712DSM-III-RMRI027627574171291.49.40.9
Getz GE2002http://dx.doi.org/10.1016/S0920-9964(01)00210-91212DSM-IVMRI029.28.730.77.5431212nsnsnsnsnsnsnsns11.71.89.91.3
Strakowski SM2002http://ajp.psychiatryonline.org/cgi/content/full/159/11/18411832DSM-IVMRI0226246716181612.41.5121.3
Strakowski SM2002http://ajp.psychiatryonline.org/cgi/content/full/159/11/18411732DSM-IVMRI02562461116171611.81.5121.3
Beyer JL (A)2004Wiley InterScience: Journal: Abstract3635DSM-IVMRI058.87.9163.25.35242236353.650.63.860.483.90.754.140.547.541.2680.93
DelBello MP2004Magnetic resonance imaging analysis of amygdala and other subcortical brain regions in adolescents with bipolar disorder - Bipolar Disorders, Vol 6, Issue 1, pp. 43-52 (Full Text)2320DSM-IVMRI016.32.417.21.999232060.85.90.76.20.96.10.812.21.712.11.4
Chang K (A)2005http://meta.wkhealth.com/pt/pt-core/template-journal/lwwgateway/media/landingpage.htm?issn=0890-8567&volume=44&issue=6&spage=5652020DSM-IVMRI014.62.814.12.84420204.670.464.560.724.830.454.820.659.510.819.381.33
Ahn MS2007http://dx.doi.org/10.1016/j.jad.2007.04.0154622DSM-IVMRI011.32.711.12.7201046228.340.978.560.9

Interpreted data and analysis

Study Experimentals Controls Effects
Mean SD Events N Mean SD Events NSDpooled Effect SE CI Z P Weight WeightDSL
Strakowski SM (B) 1993 5.900000 0.900000 nan 17 5.500000 0.700000 nan 160.809420 0.482 0.354 -0.212 1.176 1.362 0.173 7.979384 6.727% 4.890181 7.592%
Aylward EH (Females) 1994 4042.700000 987.600000 nan 14 4375.000000 974.300000 nan 13981.238498 -0.328 0.388 -1.089 0.432 -0.846 0.398 6.636144 5.595% 4.350505 6.754%
Aylward EH (Males) 1994 4625.400000 1008.500000 nan 16 3780.700000 916.200000 nan 17961.967788 0.857 0.366 0.139 1.574 2.341 0.019 7.465426 6.294% 4.692208 7.284%
Dupont RM (A) 1995 1808.810000 259.720000 nan 36 1806.350000 243.730000 nan 26253.180257 0.010 0.257 -0.495 0.514 0.037 0.970 15.096594 12.728% 6.877175 10.677%
Sax KW 1999 9.000000 1.400000 nan 17 9.400000 0.900000 nan 121.221262 -0.318 0.380 -1.063 0.426 -0.838 0.402 6.935827 5.848% 4.477331 6.951%
Getz GE 2002 11.700000 1.800000 nan 12 9.900000 1.300000 nan 121.570032 1.107 0.444 0.237 1.977 2.493 0.013 5.070790 4.275% 3.618254 5.617%
Strakowski SM 2002 12.400000 1.500000 nan 18 12.000000 1.300000 nan 161.409787 0.277 0.345 -0.400 0.954 0.802 0.423 8.379976 7.065% 5.037770 7.821%
Strakowski SM 2002 11.800000 1.500000 nan 17 12.000000 1.300000 nan 161.406781 -0.139 0.349 -0.822 0.545 -0.398 0.691 8.219998 6.930% 4.979510 7.731%
Beyer JL (A) 2004 7.540000 1.260000 nan 36 8.000000 0.930000 nan 351.109724 -0.410 0.240 -0.880 0.060 -1.708 0.088 17.360347 14.637% 7.311493 11.351%
DelBello MP 2004 12.200000 1.700000 nan 23 12.100000 1.400000 nan 201.568128 0.063 0.306 -0.537 0.662 0.205 0.838 10.691937 9.014% 5.790493 8.990%
Chang K (A) 2005 9.510000 0.810000 nan 20 9.380000 1.330000 nan 201.101136 0.116 0.317 -0.505 0.736 0.366 0.715 9.981468 8.415% 5.575563 8.656%
Ahn MS 2007 8.340000 0.970000 nan 46 8.560000 0.900000 nan 220.948288 -0.229 0.260 -0.739 0.280 -0.882 0.378 14.791971 12.471% 6.813257 10.577%
Meta-analysis (fixed effect) 272 225 0.035 0.092 -0.145 0.215 0.377 0.706 100%
Meta-analysis (random effects, DSL) 0.074 0.125 -0.171 0.318 0.591 0.554 100%
σa: 0.281369 Q: 19.497690 dof: 11.0 P-value: 0.053

Forest plot

-2 -1 0 1 2 Strakowski SM (B) 0.000000 Aylward EH (Females) 1.000000 Aylward EH (Males) 2.000000 Dupont RM (A) 3.000000 Sax KW 4.000000 Getz GE 5.000000 Strakowski SM 6.000000 Strakowski SM 7.000000 Beyer JL (A) 8.000000 DelBello MP 9.000000 Chang K (A) 10.000000 Ahn MS 11.000000 Meta-analysis (fixed effect) Meta-analysis (random effects)

Funnel plot

Effect size Standard error -0.50 -1.00 -1.50 -2.00 0.50 1.00 1.50 2.00 0.20 0.40 0.60 0.80

Warning

Column not matched "number_of_experimental_events". Column not matched "number_of_control_events".

Meta-analysis

This webservice will download a specified page from the Brede Wiki. The page should contain a comma-separated values (CSV) file with information for a meta-analysis. Study effect sizes and meta-analytic effect sizes will be computed.

The CSV file should provide information about the two groups: "experimentals" and "controls". The information you need to supply depends on whether your data is categorical (binary) or continuous:

You will usually need to specify the column names used for the data, but an automated guess will be performed if columns are not specified.

Symbols

M: mean, SD: standard deviation of data, SDpooled: Pooled standard deviation of data, N: number of data (subjects, etc.), MD: mean difference, SMD: standardized mean difference, CI: 95% confidence interval.

Examples

Acknowledgment

Matthew Kempton. Lundbeck Foundation Center for Integrated Molecular Brain Imaging (CIMBI)
Finn Årup Nielsen, CIMBI, DTU Informatics.