Brede meta-analysis


DTU Informatics >>> Neuroinformatics > Services > Brede meta-analysis

Input

Brede Wiki CSV title: 


Column names Number Mean SD Events
Experimentals:
Controls:

Go to: Article | Data | CSV

Original data

TitleFirst AuthorYearLink to paperBipolars numberControls, number ofDiagnosisMethodCT basedAge BipolarsSD Age BipolarsAge ControlsSD Age ControlsFemale BPsFemale CtrlsNumber of bipolarsNumber of controlsBipolar (left)Bipolar SD (left)Control (left)Control SD (left)Bipolar (Right)Bipolar SD (right)Controls (right)Controls SD (right)Bipolars meanBipolars SDControls MeanControls SD
Structural brain abnormalities in first-episode maniaStrakowski SM (B)1993http://dx.doi.org/10.1016/0006-3223(93)90098-X1716DSM-III-RMRI028.46.830.97.3109171611.81.411.51.2
Dupont RM (A)1995See Sept 1995 p747, Archives of General Psychiatry3626DSM-III-RMRI036.610.839.19.4121136261904.81343.061716.85293.02
Strakowski SM1999http://archpsyc.ama-assn.org/cgi/content/full/56/3/2542422DSM-III-RMRI02762867924227.71.26.90.97.416.60.815.12.213.51.7
Caetano SC2001ScienceDirect - Psychiatry Research: Neuroimaging : MRI study of thalamic volumes in bipolar and unipolar patients and healthy individuals2539DSM-IVMRI034.49.836.69.7101425393.521.233.370.883.511.293.481.027.032.426.841.68
Getz GE2002http://dx.doi.org/10.1016/S0920-9964(01)00210-91212DSM-IVMRI029.28.730.77.5431212nsnsnsnsnsnsnsns11.71.812.31.5
Strakowski SM2002http://ajp.psychiatryonline.org/cgi/content/full/159/11/18411832DSM-IVMRI02262467161816121.212.31.6
Strakowski SM2002http://ajp.psychiatryonline.org/cgi/content/full/159/11/18411732DSM-IVMRI02562461116171611.6212.31.6
DelBello MP2004Magnetic resonance imaging analysis of amygdala and other subcortical brain regions in adolescents with bipolar disorder - Bipolar Disorders, Vol 6, Issue 1, pp. 43-52 (Full Text)2320DSM-IVMRI016.32.417.21.99923205.815.90.860.96.10.911.81.812.11.6
Chang K (A)2005http://meta.wkhealth.com/pt/pt-core/template-journal/lwwgateway/media/landingpage.htm?issn=0890-8567&volume=44&issue=6&spage=5652020DSM-IVMRI014.62.814.12.84420208.070.598.180.768.070.598.260.7716.141.1416.431.5
Frazier JA (A)2005http://ajp.psychiatryonline.org/cgi/content/full/162/7/12564320DSM-IVMRI011.32.7112.62084320nsnsnsnsnsnsnsns15.741.1416.581.16

Interpreted data and analysis

Study Experimentals Controls Effects
Mean SD Events N Mean SD Events NSDpooled Effect SE CI Z P Weight WeightDSL
Strakowski SM (B) 1993 11.800000 1.400000 nan 17 11.500000 1.200000 nan 161.307053 0.224 0.350 -0.461 0.909 0.641 0.522 8.184225 7.847% 3.859937 9.150%
Dupont RM (A) 1995 1904.810000 343.060000 nan 36 1716.850000 293.020000 nan 26323.153053 0.574 0.263 0.059 1.089 2.185 0.029 14.475953 13.879% 4.855184 11.509%
Strakowski SM 1999 15.100000 2.200000 nan 24 13.500000 1.700000 nan 221.977200 0.795 0.308 0.192 1.398 2.585 0.010 10.566216 10.131% 4.319158 10.239%
Caetano SC 2001 7.030000 2.420000 nan 25 6.840000 1.680000 nan 391.999213 0.094 0.256 -0.409 0.596 0.366 0.714 15.217364 14.590% 4.935840 11.701%
Getz GE 2002 11.700000 1.800000 nan 12 12.300000 1.500000 nan 121.656804 -0.350 0.412 -1.157 0.458 -0.849 0.396 5.892266 5.649% 3.261586 7.732%
Strakowski SM 2002 12.000000 1.200000 nan 18 12.300000 1.600000 nan 161.401785 -0.209 0.345 -0.884 0.467 -0.606 0.544 8.418796 8.072% 3.911335 9.272%
Strakowski SM 2002 11.600000 2.000000 nan 17 12.300000 1.600000 nan 161.817478 -0.376 0.352 -1.065 0.314 -1.068 0.285 8.080622 7.748% 3.836736 9.095%
DelBello MP 2004 11.800000 1.800000 nan 23 12.100000 1.600000 nan 201.710227 -0.172 0.306 -0.773 0.428 -0.562 0.574 10.654417 10.215% 4.333824 10.274%
Chang K (A) 2005 16.140000 1.140000 nan 20 16.430000 1.500000 nan 201.332216 -0.213 0.317 -0.835 0.408 -0.673 0.501 9.937277 9.528% 4.210233 9.981%
Frazier JA (A) 2005 15.740000 1.140000 nan 43 16.580000 1.160000 nan 201.146267 -0.724 0.279 -1.270 -0.177 -2.597 0.009 12.871569 12.341% 4.660354 11.048%
Meta-analysis (fixed effect) 235 207 -0.001 0.098 -0.193 0.191 -0.014 0.989 100%
Meta-analysis (random effects, DSL) -0.021 0.154 -0.322 0.281 -0.133 0.894 100%
σa: 0.369980 Q: 21.743275 dof: 9.0 P-value: 0.010

Forest plot

-2 -1 0 1 2 Strakowski SM (B) 0.000000 Dupont RM (A) 1.000000 Strakowski SM 2.000000 Caetano SC 3.000000 Getz GE 4.000000 Strakowski SM 5.000000 Strakowski SM 6.000000 DelBello MP 7.000000 Chang K (A) 8.000000 Frazier JA (A) 9.000000 Meta-analysis (fixed effect) Meta-analysis (random effects)

Funnel plot

Effect size Standard error -0.20 -0.40 -0.60 -0.80 0.20 0.40 0.60 0.80 0.20 0.40 0.60 0.80

Warning

Column not matched "number_of_experimental_events". Column not matched "number_of_control_events".

Meta-analysis

This webservice will download a specified page from the Brede Wiki. The page should contain a comma-separated values (CSV) file with information for a meta-analysis. Study effect sizes and meta-analytic effect sizes will be computed.

The CSV file should provide information about the two groups: "experimentals" and "controls". The information you need to supply depends on whether your data is categorical (binary) or continuous:

You will usually need to specify the column names used for the data, but an automated guess will be performed if columns are not specified.

Symbols

M: mean, SD: standard deviation of data, SDpooled: Pooled standard deviation of data, N: number of data (subjects, etc.), MD: mean difference, SMD: standardized mean difference, CI: 95% confidence interval.

Examples

Acknowledgment

Matthew Kempton. Lundbeck Foundation Center for Integrated Molecular Brain Imaging (CIMBI)
Finn Årup Nielsen, CIMBI, DTU Informatics.