Brede meta-analysis


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Input

Brede Wiki CSV title: 


Column names Number Mean SD Events
Experimentals:
Controls:

Go to: Article | Data | CSV

Original data

First AuthorYearSubgroupNumber of PatientsNumber of ControlsPatient MeanPatient SDControl MeanControl SDPatient Age% Female PatientsAge of OnsetHam-D rating scaleAntidepressants %Mood stabilizers %Antipsychotics %Drug Free %ImagingMRI Field Strength (T)Slice Thickness (mm)PMID
Axelson DA199319304.110.774.060.7946.773.734MRI1.558341769
Pantel J199719134.470.714.620.772.478.964.226.7MRI1.51.259089060
McIntosh AM20019294465521449548343.5655.6MRI11.8811200955

Interpreted data and analysis

Study Experimentals Controls Effects
Mean SD Events N Mean SD Events NSDpooled Effect SE CI Z P Weight WeightDSL
Axelson DA 1993 4.110000 0.770000 nan 19 4.060000 0.790000 nan 300.782401 0.063 0.293 -0.512 0.638 0.214 0.830 11.626719 44.434% 11.626719 44.434%
Pantel J 1997 4.470000 0.710000 nan 19 4.620000 0.700000 nan 130.706017 -0.207 0.361 -0.915 0.500 -0.574 0.566 7.673482 29.326% 7.673482 29.326%
McIntosh AM 2001 4465.000000 521.000000 nan 9 4495.000000 483.000000 nan 29491.698304 -0.060 0.382 -0.808 0.688 -0.157 0.876 6.865951 26.240% 6.865951 26.240%
Meta-analysis (fixed effect) 47 72 -0.048 0.195 -0.432 0.335 -0.248 0.804 100%
Meta-analysis (random effects, DSL) -0.048 0.195 -0.432 0.335 -0.248 0.804 100%
σa: 0.000000 Q: 0.338130 dof: 2.0 P-value: 0.844

Forest plot

-2 -1 0 1 2 Axelson DA 0.000000 Pantel J 1.000000 McIntosh AM 2.000000 Meta-analysis (fixed effect) Meta-analysis (random effects)

Funnel plot

Effect size Standard error -0.08 -0.16 -0.24 -0.32 0.08 0.16 0.24 0.32 0.10 0.20 0.30 0.40

Warning

Column not matched "number_of_experimental_events". Column not matched "number_of_control_events".

Meta-analysis

This webservice will download a specified page from the Brede Wiki. The page should contain a comma-separated values (CSV) file with information for a meta-analysis. Study effect sizes and meta-analytic effect sizes will be computed.

The CSV file should provide information about the two groups: "experimentals" and "controls". The information you need to supply depends on whether your data is categorical (binary) or continuous:

You will usually need to specify the column names used for the data, but an automated guess will be performed if columns are not specified.

Symbols

M: mean, SD: standard deviation of data, SDpooled: Pooled standard deviation of data, N: number of data (subjects, etc.), MD: mean difference, SMD: standardized mean difference, CI: 95% confidence interval.

Examples

Acknowledgment

Matthew Kempton. Lundbeck Foundation Center for Integrated Molecular Brain Imaging (CIMBI)
Finn Årup Nielsen, CIMBI, DTU Informatics.