Brede meta-analysis


DTU Informatics >>> Neuroinformatics > Services > Brede meta-analysis

Input

Brede Wiki CSV title: 


Column names Number Mean SD Events
Experimentals:
Controls:

Go to: Article | Data | CSV

Original data

First AuthorYearSubgroupNumber of PatientsNumber of ControlsPatient MeanPatient SDControl MeanControl SDPatient Age% Female PatientsAge of OnsetHam-D rating scaleAntidepressants %Mood stabilizers %Antipsychotics %Drug Free %ImagingMRI Field Strength (T)Slice Thickness (mm)PMID
Axelson DA199319304.360.884.30.7946.773.734MRI1.558341769
Pantel J199719134.580.764.750.6172.478.964.226.7MRI1.51.259089060
McIntosh AM20019294931547492265443.5655.6MRI11.8811200955

Interpreted data and analysis

Study Experimentals Controls Effects
Mean SD Events N Mean SD Events NSDpooled Effect SE CI Z P Weight WeightDSL
Axelson DA 1993 4.360000 0.880000 nan 19 4.300000 0.790000 nan 300.825628 0.072 0.293 -0.503 0.646 0.244 0.807 11.624981 44.449% 11.624981 44.449%
Pantel J 1997 4.580000 0.760000 nan 19 4.750000 0.610000 nan 130.703847 -0.235 0.361 -0.944 0.473 -0.652 0.515 7.660346 29.290% 7.660346 29.290%
McIntosh AM 2001 4931.000000 547.000000 nan 9 4922.000000 654.000000 nan 29631.790225 0.014 0.382 -0.734 0.762 0.037 0.971 6.868286 26.261% 6.868286 26.261%
Meta-analysis (fixed effect) 47 72 -0.034 0.196 -0.417 0.350 -0.171 0.864 100%
Meta-analysis (random effects, DSL) -0.034 0.196 -0.417 0.350 -0.171 0.864 100%
σa: 0.000000 Q: 0.456032 dof: 2.0 P-value: 0.796

Forest plot

-2 -1 0 1 2 Axelson DA 0.000000 Pantel J 1.000000 McIntosh AM 2.000000 Meta-analysis (fixed effect) Meta-analysis (random effects)

Funnel plot

Effect size Standard error -0.08 -0.16 -0.24 -0.32 0.08 0.16 0.24 0.32 0.10 0.20 0.30 0.40

Warning

Column not matched "number_of_experimental_events". Column not matched "number_of_control_events".

Meta-analysis

This webservice will download a specified page from the Brede Wiki. The page should contain a comma-separated values (CSV) file with information for a meta-analysis. Study effect sizes and meta-analytic effect sizes will be computed.

The CSV file should provide information about the two groups: "experimentals" and "controls". The information you need to supply depends on whether your data is categorical (binary) or continuous:

You will usually need to specify the column names used for the data, but an automated guess will be performed if columns are not specified.

Symbols

M: mean, SD: standard deviation of data, SDpooled: Pooled standard deviation of data, N: number of data (subjects, etc.), MD: mean difference, SMD: standardized mean difference, CI: 95% confidence interval.

Examples

Acknowledgment

Matthew Kempton. Lundbeck Foundation Center for Integrated Molecular Brain Imaging (CIMBI)
Finn Årup Nielsen, CIMBI, DTU Informatics.