Brede meta-analysis


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Input

Brede Wiki CSV title: 


Column names Number Mean SD Events
Experimentals:
Controls:

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Original data

First AuthorYearSubgroupNumber of PatientsNumber of ControlsPatient MeanPatient SDControl MeanControl SDPatient Age% Female PatientsAge of OnsetHam-D rating scaleAntidepressants %Mood stabilizers %Antipsychotics %Drug Free %ImagingMRI Field Strength (T)Slice Thickness (mm)PMID
Axelson DA199319308.471.5657138958.361.49891961146.773.734MRI1.558341769
Pantel J199719139.051.3946540799.371.24310096172.478.964.226.7MRI1.51.259089060
Ashtari M1999404679591166826299074.370.061.526.1MRI13.110405084
McIntosh AM200192993961013.22712294171080.007543.5655.6MRI11.8811200955

Interpreted data and analysis

Study Experimentals Controls Effects
Mean SD Events N Mean SD Events NSDpooled Effect SE CI Z P Weight WeightDSL
Axelson DA 1993 8.470000 1.565714 nan 19 8.360000 1.498920 nan 301.524846 0.071 0.293 -0.504 0.646 0.242 0.809 11.625093 24.559% 11.625093 24.559%
Pantel J 1997 9.050000 1.394654 nan 19 9.370000 1.243101 nan 131.336097 -0.233 0.361 -0.942 0.475 -0.646 0.518 7.661315 16.185% 7.661315 16.185%
Ashtari M 1999 7959.000000 1166.000000 nan 40 8262.000000 990.000000 nan 461075.302748 -0.279 0.217 -0.705 0.147 -1.285 0.199 21.180024 44.745% 21.180024 44.745%
McIntosh AM 2001 9396.000000 1013.227122 nan 9 9417.000000 1080.007500 nan 291065.529175 -0.019 0.382 -0.767 0.729 -0.051 0.960 6.868163 14.510% 6.868163 14.510%
Meta-analysis (fixed effect) 87 118 -0.148 0.145 -0.433 0.137 -1.019 0.308 100%
Meta-analysis (random effects, DSL) -0.148 0.145 -0.433 0.137 -1.019 0.308 100%
σa: 0.000000 Q: 1.092088 dof: 3.0 P-value: 0.779

Forest plot

-2 -1 0 1 2 Axelson DA 0.000000 Pantel J 1.000000 Ashtari M 2.000000 McIntosh AM 3.000000 Meta-analysis (fixed effect) Meta-analysis (random effects)

Funnel plot

Effect size Standard error -0.08 -0.16 -0.24 -0.32 0.08 0.16 0.24 0.32 0.10 0.20 0.30 0.40

Warning

Column not matched "number_of_experimental_events". Column not matched "number_of_control_events".

Meta-analysis

This webservice will download a specified page from the Brede Wiki. The page should contain a comma-separated values (CSV) file with information for a meta-analysis. Study effect sizes and meta-analytic effect sizes will be computed.

The CSV file should provide information about the two groups: "experimentals" and "controls". The information you need to supply depends on whether your data is categorical (binary) or continuous:

You will usually need to specify the column names used for the data, but an automated guess will be performed if columns are not specified.

Symbols

M: mean, SD: standard deviation of data, SDpooled: Pooled standard deviation of data, N: number of data (subjects, etc.), MD: mean difference, SMD: standardized mean difference, CI: 95% confidence interval.

Examples

Acknowledgment

Matthew Kempton. Lundbeck Foundation Center for Integrated Molecular Brain Imaging (CIMBI)
Finn Årup Nielsen, CIMBI, DTU Informatics.