Brede meta-analysis


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Input

Brede Wiki CSV title: 


Column names Number Mean SD Events
Experimentals:
Controls:

Go to: Article | Data | CSV

Original data

First AuthorYearSubgroupNumber of PatientsNumber of ControlsPatient MeanPatient SDControl MeanControl SDPatient Age% Female PatientsAge of OnsetHam-D rating scaleAntidepressants %Mood stabilizers %Antipsychotics %Drug Free %ImagingMRI Field Strength (T)Slice Thickness (mm)PMID
Caetano SC200631312.410.483.020.52077.427.911.8000100MRI1.51.516414029
Lavretsky H200743410.00440.00160.00430.00170.6776.749.617.7000100MRI1.51.417463189
Frodl T (A)200878786.651.426.061.7844.751.339.623.5121010MRI1.51.518406580
Weber K200938621.370.331.260.3766.1181.637.7647MRI30.920018381

Interpreted data and analysis

Study Experimentals Controls Effects
Mean SD Events N Mean SD Events NSDpooled Effect SE CI Z P Weight WeightDSL
Caetano SC 2006 2.410000 0.480000 nan 31 3.020000 0.520000 nan 310.500400 -1.204 0.277 -1.748 -0.660 -4.338 0.000 12.987996 13.586% 2.438515 23.206%
Lavretsky H 2007 0.004400 0.001600 nan 43 0.004300 0.001000 nan 410.001341 0.074 0.218 -0.354 0.502 0.338 0.735 20.973093 21.939% 2.626246 24.992%
Frodl T (A) 2008 6.650000 1.420000 nan 78 6.060000 1.780000 nan 781.610093 0.365 0.161 0.048 0.681 2.258 0.024 38.346124 40.112% 2.784199 26.495%
Weber K 2009 1.370000 0.330000 nan 38 1.260000 0.370000 nan 620.355427 0.307 0.207 -0.099 0.713 1.482 0.138 23.290613 24.363% 2.659382 25.307%
Meta-analysis (fixed effect) 190 212 0.074 0.102 -0.127 0.274 0.721 0.471 100%
Meta-analysis (random effects, DSL) -0.087 0.308 -0.691 0.518 -0.281 0.779 100%
σa: 0.577141 Q: 25.708948 dof: 3.0 P-value: 0.000

Forest plot

-2 -1 0 1 2 Caetano SC 0.000000 Lavretsky H 1.000000 Frodl T (A) 2.000000 Weber K 3.000000 Meta-analysis (fixed effect) Meta-analysis (random effects)

Funnel plot

Effect size Standard error -0.50 -1.00 -1.50 -2.00 0.50 1.00 1.50 2.00 0.08 0.16 0.24 0.32

Warning

Column not matched "number_of_experimental_events". Column not matched "number_of_control_events".

Meta-analysis

This webservice will download a specified page from the Brede Wiki. The page should contain a comma-separated values (CSV) file with information for a meta-analysis. Study effect sizes and meta-analytic effect sizes will be computed.

The CSV file should provide information about the two groups: "experimentals" and "controls". The information you need to supply depends on whether your data is categorical (binary) or continuous:

You will usually need to specify the column names used for the data, but an automated guess will be performed if columns are not specified.

Symbols

M: mean, SD: standard deviation of data, SDpooled: Pooled standard deviation of data, N: number of data (subjects, etc.), MD: mean difference, SMD: standardized mean difference, CI: 95% confidence interval.

Examples

Acknowledgment

Matthew Kempton. Lundbeck Foundation Center for Integrated Molecular Brain Imaging (CIMBI)
Finn Årup Nielsen, CIMBI, DTU Informatics.