Brede meta-analysis


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Input

Brede Wiki CSV title: 


Column names Number Mean SD Events
Experimentals:
Controls:

Go to: Article | Data | CSV

Original data

First AuthorYearSubgroupNumber of PatientsNumber of ControlsPatient MeanPatient SDControl MeanControl SDPatient Age% Female PatientsAge of OnsetHam-D rating scaleAntidepressants %Mood stabilizers %Antipsychotics %Drug Free %ImagingMRI Field Strength (T)Slice Thickness (mm)PMID
Caetano SC200631312.520.432.850.53077.427.911.8000100MRI1.51.516414029
Lavretsky H200743410.00430.00140.00440.000770.6776.749.617.7000100MRI1.51.417463189
Frodl T (A)200878786.571.616.811.5644.751.339.623.5121010MRI1.51.518406580
Weber K200938621.390.391.370.4166.1181.637.7647MRI30.920018381

Interpreted data and analysis

Study Experimentals Controls Effects
Mean SD Events N Mean SD Events NSDpooled Effect SE CI Z P Weight WeightDSL
Caetano SC 2006 2.520000 0.430000 nan 31 2.850000 0.530000 nan 310.482597 -0.675 0.262 -1.188 -0.162 -2.581 0.010 14.610827 14.906% 10.298159 18.441%
Lavretsky H 2007 0.004300 0.001400 nan 43 0.004400 0.000700 nan 410.001115 -0.089 0.218 -0.517 0.339 -0.407 0.684 20.966388 21.391% 13.096251 23.451%
Frodl T (A) 2008 6.570000 1.610000 nan 78 6.810000 1.560000 nan 781.585197 -0.151 0.160 -0.465 0.164 -0.940 0.347 38.886804 39.674% 18.389788 32.930%
Weber K 2009 1.390000 0.390000 nan 38 1.370000 0.410000 nan 620.402566 0.049 0.206 -0.355 0.453 0.239 0.811 23.552980 24.029% 14.060779 25.178%
Meta-analysis (fixed effect) 190 212 -0.168 0.101 -0.366 0.030 -1.659 0.097 100%
Meta-analysis (random effects, DSL) -0.183 0.134 -0.445 0.080 -1.364 0.172 100%
σa: 0.169300 Q: 5.014011 dof: 3.0 P-value: 0.171

Forest plot

-2 -1 0 1 2 Caetano SC 0.000000 Lavretsky H 1.000000 Frodl T (A) 2.000000 Weber K 3.000000 Meta-analysis (fixed effect) Meta-analysis (random effects)

Funnel plot

Effect size Standard error -0.20 -0.40 -0.60 -0.80 0.20 0.40 0.60 0.80 0.08 0.16 0.24 0.32

Warning

Column not matched "number_of_experimental_events". Column not matched "number_of_control_events".

Meta-analysis

This webservice will download a specified page from the Brede Wiki. The page should contain a comma-separated values (CSV) file with information for a meta-analysis. Study effect sizes and meta-analytic effect sizes will be computed.

The CSV file should provide information about the two groups: "experimentals" and "controls". The information you need to supply depends on whether your data is categorical (binary) or continuous:

You will usually need to specify the column names used for the data, but an automated guess will be performed if columns are not specified.

Symbols

M: mean, SD: standard deviation of data, SDpooled: Pooled standard deviation of data, N: number of data (subjects, etc.), MD: mean difference, SMD: standardized mean difference, CI: 95% confidence interval.

Examples

Acknowledgment

Matthew Kempton. Lundbeck Foundation Center for Integrated Molecular Brain Imaging (CIMBI)
Finn Årup Nielsen, CIMBI, DTU Informatics.