Brede meta-analysis


DTU Informatics >>> Neuroinformatics > Services > Brede meta-analysis

Input

Brede Wiki CSV title: 


Column names Number Mean SD Events
Experimentals:
Controls:

Go to: Article | Data | CSV

Original data

First AuthorYearSubgroupNumber of PatientsNumber of ControlsPatients hyperintensityControls hyperintensityPatient Age% Female PatientsAge of OnsetHam-D rating scaleAntidepressants %Mood stabilizers %Antipsychotics %Drug Free %ImagingMRI Field Strength (T)Slice Thickness (mm)PMID
Zubenko GS1990674428873.271.662.5MRI1.552222243
Brown FW19922815441240.3MRI171575251
Guze BH19921196035970.634.9MRI0.371484908
Lesser IM1994392011760.943.620.1000100MRI1.5108080344
Dupont RM (B)199533329738.960.612.539355MRI1.558672610
Agid R200337272675556.831.4MRI2512974987
Sassi RB2003183872242.888.930000100MRI1.51.514612223
Chen CS2005392027769.966.766.521.733MRI3716223965
Iosifescu DV20068435512140.521.6MRI1.5316449707
Zanetti MV20082810253030.567.950145725MRI1.5318700214

Interpreted data and analysis

Study Experimentals Controls Effects
Mean SD Events N Mean SD Events NSDpooled Effect SE CI Z P Weight WeightDSL
Zubenko GS 1990 nan nan nan 67 nan nan nan 44nan nan nan nan  nan nan nan 0.000000 0.000% 0.000000 0.000%
Brown FW 1992 nan nan nan 28 nan nan nan 154nan nan nan nan  nan nan nan 0.000000 0.000% 0.000000 0.000%
Guze BH 1992 nan nan nan 119 nan nan nan 60nan nan nan nan  nan nan nan 0.000000 0.000% 0.000000 0.000%
Lesser IM 1994 nan nan nan 39 nan nan nan 20nan nan nan nan  nan nan nan 0.000000 0.000% 0.000000 0.000%
Dupont RM (B) 1995 nan nan nan 33 nan nan nan 32nan nan nan nan  nan nan nan 0.000000 0.000% 0.000000 0.000%
Agid R 2003 nan nan nan 37 nan nan nan 27nan nan nan nan  nan nan nan 0.000000 0.000% 0.000000 0.000%
Sassi RB 2003 nan nan nan 18 nan nan nan 38nan nan nan nan  nan nan nan 0.000000 0.000% 0.000000 0.000%
Chen CS 2005 nan nan nan 39 nan nan nan 20nan nan nan nan  nan nan nan 0.000000 0.000% 0.000000 0.000%
Iosifescu DV 2006 nan nan nan 84 nan nan nan 35nan nan nan nan  nan nan nan 0.000000 0.000% 0.000000 0.000%
Zanetti MV 2008 nan nan nan 28 nan nan nan 102nan nan nan nan  nan nan nan 0.000000 0.000% 0.000000 0.000%
Meta-analysis (fixed effect) 0 0 0.000 inf -inf inf 0.000 1.000 100%
Meta-analysis (random effects, DSL) nan inf nan  nan nan nan 100%
σa: 0.000000 Q: 0.000000 dof: -1.0 P-value: nan

Forest plot

Funnel plot

Effect size Standard error -0.50 -1.00 -1.50 -2.00 0.50 1.00 1.50 2.00 0.30 0.60 0.90 1.20

Warning

Column not matched "number_of_experimental_events". Column not matched "number_of_control_events". Column not matched "mean_experimentals". Column not matched "mean_controls". Column not matched "sd_experimentals". Column not matched "sd_controls". %d format: a number is required, not numpy.float64

Meta-analysis

This webservice will download a specified page from the Brede Wiki. The page should contain a comma-separated values (CSV) file with information for a meta-analysis. Study effect sizes and meta-analytic effect sizes will be computed.

The CSV file should provide information about the two groups: "experimentals" and "controls". The information you need to supply depends on whether your data is categorical (binary) or continuous:

You will usually need to specify the column names used for the data, but an automated guess will be performed if columns are not specified.

Symbols

M: mean, SD: standard deviation of data, SDpooled: Pooled standard deviation of data, N: number of data (subjects, etc.), MD: mean difference, SMD: standardized mean difference, CI: 95% confidence interval.

Examples

Acknowledgment

Matthew Kempton. Lundbeck Foundation Center for Integrated Molecular Brain Imaging (CIMBI)
Finn Årup Nielsen, CIMBI, DTU Informatics.