Brede meta-analysis


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Input

Brede Wiki CSV title: 


Column names Number Mean SD Events
Experimentals:
Controls:

Go to: Article | Data | CSV

Original data

First AuthorYearSubgroupNumber of PatientsNumber of ControlsPatient MeanPatient SDControl MeanControl SDPatient Age% Female PatientsAge of OnsetHam-D rating scaleAntidepressants %Mood stabilizers %Antipsychotics %Drug Free %ImagingMRI Field Strength (T)Slice Thickness (mm)PMID
Pillay SS199838204.60.74.60.638.555.320.6MRI1.5310710164
Lenze EJ (B)199924243.340.693.190.5953100.0MRI1.2510588417
Bremner JD20001616266871027675714337.5100.00.00.00.0MRI1.5310618023
McIntosh AM20019294267506433644743.5655.6MRI11.8811200955
Lacerda AL200325482.630.422.820.541.216.029.4410.90.00.00.0100.0MRI1.5514623065
Hannestad J2006182643.490.73.480.670.270.943.7MRI1.5316955447
Matsuo K200827262.420.332.530.3214.463.011.750.00.00.0100.0MRI1.51.518439110
Pizzagalli DA200926313427507343344743.1757.729.3916.00.00.00.0100.0MRI1.51.3319411368

Interpreted data and analysis

Study Experimentals Controls Effects
Mean SD Events N Mean SD Events NSDpooled Effect SE CI Z P Weight WeightDSL
Pillay SS 1998 4.600000 0.700000 nan 38 4.600000 0.600000 nan 200.667752 0.000 0.276 -0.541 0.541 0.000 1.000 13.103448 10.039% 13.103448 10.039%
Lenze EJ (B) 1999 3.340000 0.690000 nan 24 3.190000 0.590000 nan 240.641950 0.230 0.290 -0.338 0.798 0.793 0.428 11.914297 9.128% 11.914297 9.128%
Bremner JD 2000 2668.000000 710.000000 nan 16 2767.000000 571.000000 nan 16644.259653 -0.150 0.354 -0.844 0.544 -0.423 0.672 7.974494 6.110% 7.974494 6.110%
McIntosh AM 2001 4267.000000 506.000000 nan 9 4336.000000 447.000000 nan 29460.764461 -0.147 0.382 -0.895 0.602 -0.384 0.701 6.853568 5.251% 6.853568 5.251%
Lacerda AL 2003 2.630000 0.420000 nan 25 2.820000 0.500000 nan 480.474469 -0.396 0.249 -0.884 0.092 -1.592 0.111 16.136878 12.363% 16.136878 12.363%
Hannestad J 2006 3.490000 0.700000 nan 182 3.480000 0.600000 nan 640.675599 0.015 0.145 -0.270 0.300 0.102 0.919 47.348585 36.277% 47.348585 36.277%
Matsuo K 2008 2.420000 0.330000 nan 27 2.530000 0.320000 nan 260.325136 -0.333 0.277 -0.876 0.209 -1.204 0.229 13.049569 9.998% 13.049569 9.998%
Pizzagalli DA 2009 3427.000000 507.000000 nan 26 3433.000000 447.000000 nan 31475.212775 -0.012 0.266 -0.534 0.509 -0.047 0.963 14.140059 10.834% 14.140059 10.834%
Meta-analysis (fixed effect) 347 258 -0.074 0.088 -0.246 0.097 -0.847 0.397 100%
Meta-analysis (random effects, DSL) -0.074 0.088 -0.246 0.097 -0.847 0.397 100%
σa: 0.000000 Q: 4.232888 dof: 7.0 P-value: 0.753

Forest plot

-2 -1 0 1 2 Pillay SS 0.000000 Lenze EJ (B) 1.000000 Bremner JD 2.000000 McIntosh AM 3.000000 Lacerda AL 4.000000 Hannestad J 5.000000 Matsuo K 6.000000 Pizzagalli DA 7.000000 Meta-analysis (fixed effect) Meta-analysis (random effects)

Funnel plot

Effect size Standard error -0.10 -0.20 -0.30 -0.40 0.10 0.20 0.30 0.40 0.10 0.20 0.30 0.40

Warning

Column not matched "number_of_experimental_events". Column not matched "number_of_control_events".

Meta-analysis

This webservice will download a specified page from the Brede Wiki. The page should contain a comma-separated values (CSV) file with information for a meta-analysis. Study effect sizes and meta-analytic effect sizes will be computed.

The CSV file should provide information about the two groups: "experimentals" and "controls". The information you need to supply depends on whether your data is categorical (binary) or continuous:

You will usually need to specify the column names used for the data, but an automated guess will be performed if columns are not specified.

Symbols

M: mean, SD: standard deviation of data, SDpooled: Pooled standard deviation of data, N: number of data (subjects, etc.), MD: mean difference, SMD: standardized mean difference, CI: 95% confidence interval.

Examples

Acknowledgment

Matthew Kempton. Lundbeck Foundation Center for Integrated Molecular Brain Imaging (CIMBI)
Finn Årup Nielsen, CIMBI, DTU Informatics.