Brede meta-analysis


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Input

Brede Wiki CSV title: 


Column names Number Mean SD Events
Experimentals:
Controls:

Go to: Article | Data | CSV

Original data

First AuthorYearSubgroupNumber of PatientsNumber of ControlsPatient MeanPatient SDControl MeanControl SDPatient Age% Female PatientsAge of OnsetHam-D rating scaleAntidepressants %Mood stabilizers %Antipsychotics %Drug Free %ImagingMRI Field Strength (T)Slice Thickness (mm)PMID
Shah SA199227361.090.41.140.557.659.3MRI041642132
McIntosh AM200192965124967540243.5655.6MRI01.8811200955
Supprian T200410103.361.352.680.5848.960.00.0MRI0415465296

Interpreted data and analysis

Study Experimentals Controls Effects
Mean SD Events N Mean SD Events NSDpooled Effect SE CI Z P Weight WeightDSL
Shah SA 1992 1.090000 0.400000 nan 27 1.140000 0.500000 nan 360.460043 -0.107 0.255 -0.607 0.392 -0.421 0.674 15.405385 57.093% 14.988692 56.684%
McIntosh AM 2001 651.000000 249.000000 nan 9 675.000000 402.000000 nan 29373.456825 -0.063 0.382 -0.811 0.685 -0.165 0.869 6.865681 25.445% 6.781658 25.647%
Supprian T 2004 3.360000 1.350000 nan 10 2.680000 0.580000 nan 101.038966 0.627 0.461 -0.276 1.530 1.361 0.174 4.711798 17.462% 4.672072 17.669%
Meta-analysis (fixed effect) 46 75 0.032 0.193 -0.345 0.409 0.167 0.867 100%
Meta-analysis (random effects, DSL) 0.034 0.194 -0.347 0.415 0.174 0.862 100%
σa: 0.042481 Q: 2.028184 dof: 2.0 P-value: 0.363

Forest plot

-2 -1 0 1 2 Shah SA 0.000000 McIntosh AM 1.000000 Supprian T 2.000000 Meta-analysis (fixed effect) Meta-analysis (random effects)

Funnel plot

Effect size Standard error -0.20 -0.40 -0.60 -0.80 0.20 0.40 0.60 0.80 0.20 0.40 0.60 0.80

Warning

Column not matched "number_of_experimental_events". Column not matched "number_of_control_events".

Meta-analysis

This webservice will download a specified page from the Brede Wiki. The page should contain a comma-separated values (CSV) file with information for a meta-analysis. Study effect sizes and meta-analytic effect sizes will be computed.

The CSV file should provide information about the two groups: "experimentals" and "controls". The information you need to supply depends on whether your data is categorical (binary) or continuous:

You will usually need to specify the column names used for the data, but an automated guess will be performed if columns are not specified.

Symbols

M: mean, SD: standard deviation of data, SDpooled: Pooled standard deviation of data, N: number of data (subjects, etc.), MD: mean difference, SMD: standardized mean difference, CI: 95% confidence interval.

Examples

Acknowledgment

Matthew Kempton. Lundbeck Foundation Center for Integrated Molecular Brain Imaging (CIMBI)
Finn Årup Nielsen, CIMBI, DTU Informatics.