Brede meta-analysis


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Input

Brede Wiki CSV title: 


Column names Number Mean SD Events
Experimentals:
Controls:

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Original data

First AuthorYearSubgroupNumber of PatientsNumber of ControlsPatient MeanPatient SDControl MeanControl SDPatient Age% Female PatientsAge of OnsetHam-D rating scaleAntidepressants %Mood stabilizers %Antipsychotics %Drug Free %ImagingMRI Field Strength (T)Slice Thickness (mm)PMID
Nolan CL2002222225.947.6625.024.4754.512.18MRI1.51.511825139
Salokangas RK2002psychosis209.535.226.0336.685.783460.0MRI1.55.412271802
Salokangas RK2002no psychosis179.540.136.9136.685.7838.452.9MRI1.55.412271802
Lavretsky H2004females32200.05220.00450.05510.004770.5100.048.5000100MRI1.51.415545334
Lavretsky H2004males9210.05210.00540.05220.005270.50.048.5000100MRI1.51.415545334
Frodl T2006343471.65.271.86.145.544.138.824.891129MRI1.516951734

Interpreted data and analysis

Study Experimentals Controls Effects
Mean SD Events N Mean SD Events NSDpooled Effect SE CI Z P Weight WeightDSL
Nolan CL 2002 25.940000 7.660000 nan 22 25.020000 4.470000 nan 226.271224 0.144 0.302 -0.448 0.736 0.477 0.633 10.968744 18.824% 8.418624 18.831%
Salokangas RK 2002 35.220000 6.030000 nan 20 36.680000 5.780000 nan 105.953848 -0.238 0.395 -1.014 0.537 -0.603 0.546 6.394859 10.974% 5.435027 12.157%
Salokangas RK 2002 40.130000 6.910000 nan 17 36.680000 5.780000 nan 106.540115 0.511 0.412 -0.297 1.319 1.240 0.215 5.886562 10.102% 5.063431 11.326%
Lavretsky H 2004 0.052200 0.004500 nan 32 0.055100 0.004700 nan 200.004577 -0.624 0.292 -1.196 -0.052 -2.137 0.033 11.723117 20.119% 8.856011 19.809%
Lavretsky H 2004 0.052100 0.005400 nan 9 0.052200 0.005200 nan 210.005258 -0.019 0.398 -0.799 0.762 -0.046 0.963 6.299739 10.811% 5.366165 12.003%
Frodl T 2006 71.600000 5.200000 nan 34 71.800000 6.100000 nan 345.667892 -0.035 0.243 -0.510 0.441 -0.144 0.886 16.997256 29.170% 11.567495 25.874%
Meta-analysis (fixed effect) 134 116 -0.085 0.131 -0.342 0.172 -0.650 0.516 100%
Meta-analysis (random effects, DSL) -0.079 0.150 -0.372 0.214 -0.527 0.598 100%
σa: 0.166181 Q: 6.295511 dof: 5.0 P-value: 0.279

Forest plot

-2 -1 0 1 2 Nolan CL 0.000000 Salokangas RK 1.000000 Salokangas RK 2.000000 Lavretsky H 3.000000 Lavretsky H 4.000000 Frodl T 5.000000 Meta-analysis (fixed effect) Meta-analysis (random effects)

Funnel plot

Effect size Standard error -0.20 -0.40 -0.60 -0.80 0.20 0.40 0.60 0.80 0.20 0.40 0.60 0.80

Warning

Column not matched "number_of_experimental_events". Column not matched "number_of_control_events".

Meta-analysis

This webservice will download a specified page from the Brede Wiki. The page should contain a comma-separated values (CSV) file with information for a meta-analysis. Study effect sizes and meta-analytic effect sizes will be computed.

The CSV file should provide information about the two groups: "experimentals" and "controls". The information you need to supply depends on whether your data is categorical (binary) or continuous:

You will usually need to specify the column names used for the data, but an automated guess will be performed if columns are not specified.

Symbols

M: mean, SD: standard deviation of data, SDpooled: Pooled standard deviation of data, N: number of data (subjects, etc.), MD: mean difference, SMD: standardized mean difference, CI: 95% confidence interval.

Examples

Acknowledgment

Matthew Kempton. Lundbeck Foundation Center for Integrated Molecular Brain Imaging (CIMBI)
Finn Årup Nielsen, CIMBI, DTU Informatics.