Brede meta-analysis


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Input

Brede Wiki CSV title: 


Column names Number Mean SD Events
Experimentals:
Controls:

Go to: Article | Data | CSV

Original data

First AuthorYearSubgroupNumber of PatientsNumber of ControlsPatient MeanPatient SDControl MeanControl SDPatient Age% Female PatientsAge of OnsetHam-D rating scaleAntidepressants %Mood stabilizers %Antipsychotics %Drug Free %ImagingMRI Field Strength (T)Slice Thickness (mm)PMID
Bremner JD200215203381254952304333.3100MRI1.5311958777
Andreescu C200871320.450.080.50.1172.269.052.318.3171MRI1.51.518075490
Elderkin-Thompson V (B)200826230.2940.0680.3520.042042.349.817.900MRI1.51.418819162

Interpreted data and analysis

Study Experimentals Controls Effects
Mean SD Events N Mean SD Events NSDpooled Effect SE CI Z P Weight WeightDSL
Bremner JD 2002 338.000000 125.000000 nan 15 495.000000 230.000000 nan 20192.578201 -0.797 0.356 -1.495 -0.098 -2.236 0.025 7.881370 19.713% 7.881370 19.713%
Andreescu C 2008 0.450000 0.080000 nan 71 0.500000 0.110000 nan 320.090275 -0.550 0.216 -0.974 -0.125 -2.540 0.011 21.340194 53.376% 21.340194 53.376%
Elderkin-Thompson V (B) 2008 0.294000 0.068000 nan 26 0.352000 0.042000 nan 230.057317 -0.996 0.305 -1.593 -0.398 -3.266 0.001 10.759587 26.912% 10.759587 26.912%
Meta-analysis (fixed effect) 112 75 -0.718 0.158 -1.028 -0.408 -4.543 0.000 100%
Meta-analysis (random effects, DSL) -0.718 0.158 -1.028 -0.408 -4.543 0.000 100%
σa: 0.000000 Q: 1.482426 dof: 2.0 P-value: 0.477

Forest plot

-2 -1 0 1 2 Bremner JD 0.000000 Andreescu C 1.000000 Elderkin-Thompson V (B) 2.000000 Meta-analysis (fixed effect) Meta-analysis (random effects)

Funnel plot

Effect size Standard error -0.30 -0.60 -0.90 -1.20 0.30 0.60 0.90 1.20 0.10 0.20 0.30 0.40

Warning

Column not matched "number_of_experimental_events". Column not matched "number_of_control_events".

Meta-analysis

This webservice will download a specified page from the Brede Wiki. The page should contain a comma-separated values (CSV) file with information for a meta-analysis. Study effect sizes and meta-analytic effect sizes will be computed.

The CSV file should provide information about the two groups: "experimentals" and "controls". The information you need to supply depends on whether your data is categorical (binary) or continuous:

You will usually need to specify the column names used for the data, but an automated guess will be performed if columns are not specified.

Symbols

M: mean, SD: standard deviation of data, SDpooled: Pooled standard deviation of data, N: number of data (subjects, etc.), MD: mean difference, SMD: standardized mean difference, CI: 95% confidence interval.

Examples

Acknowledgment

Matthew Kempton. Lundbeck Foundation Center for Integrated Molecular Brain Imaging (CIMBI)
Finn Årup Nielsen, CIMBI, DTU Informatics.