Brede meta-analysis


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Input

Brede Wiki CSV title: 


Column names Number Mean SD Events
Experimentals:
Controls:

Go to: Article | Data | CSV

Original data

First AuthorYearSubgroupNumber of PatientsNumber of ControlsPatient MeanPatient SDControl MeanControl SDPatient Age% Female PatientsAge of OnsetHam-D rating scaleAntidepressants %Mood stabilizers %Antipsychotics %Drug Free %ImagingMRI Field Strength (T)Slice Thickness (mm)PMID
Lacerda AL200431345.10.875.681.41077.427.9414.07100MRI1.51.514960287
Janssen J200428414.61.084.541.320100.033.0461251421MRI1.51.215576058
Chen HH200827266.21.6130716045.61.23369364114.463.011.7520.1000100MRI1.51.519108659

Interpreted data and analysis

Study Experimentals Controls Effects
Mean SD Events N Mean SD Events NSDpooled Effect SE CI Z P Weight WeightDSL
Lacerda AL 2004 5.100000 0.870000 nan 31 5.680000 1.410000 nan 341.183982 -0.484 0.252 -0.978 0.010 -1.919 0.055 15.726186 34.708% 5.208898 33.874%
Janssen J 2004 4.600000 1.080000 nan 28 4.540000 1.320000 nan 411.228935 0.048 0.245 -0.432 0.529 0.197 0.844 16.632725 36.709% 5.304662 34.497%
Chen HH 2008 6.200000 1.613072 nan 27 5.600000 1.233694 nan 261.439649 0.411 0.278 -0.134 0.955 1.478 0.140 12.950536 28.582% 4.863627 31.629%
Meta-analysis (fixed effect) 86 101 -0.033 0.149 -0.324 0.258 -0.222 0.825 100%
Meta-analysis (random effects, DSL) -0.017 0.255 -0.517 0.482 -0.068 0.945 100%
σa: 0.358317 Q: 5.857357 dof: 2.0 P-value: 0.053

Forest plot

-2 -1 0 1 2 Lacerda AL 0.000000 Janssen J 1.000000 Chen HH 2.000000 Meta-analysis (fixed effect) Meta-analysis (random effects)

Funnel plot

Effect size Standard error -0.20 -0.40 -0.60 -0.80 0.20 0.40 0.60 0.80 0.08 0.16 0.24 0.32

Warning

Column not matched "number_of_experimental_events". Column not matched "number_of_control_events".

Meta-analysis

This webservice will download a specified page from the Brede Wiki. The page should contain a comma-separated values (CSV) file with information for a meta-analysis. Study effect sizes and meta-analytic effect sizes will be computed.

The CSV file should provide information about the two groups: "experimentals" and "controls". The information you need to supply depends on whether your data is categorical (binary) or continuous:

You will usually need to specify the column names used for the data, but an automated guess will be performed if columns are not specified.

Symbols

M: mean, SD: standard deviation of data, SDpooled: Pooled standard deviation of data, N: number of data (subjects, etc.), MD: mean difference, SMD: standardized mean difference, CI: 95% confidence interval.

Examples

Acknowledgment

Matthew Kempton. Lundbeck Foundation Center for Integrated Molecular Brain Imaging (CIMBI)
Finn Årup Nielsen, CIMBI, DTU Informatics.