Brede meta-analysis


DTU Informatics >>> Neuroinformatics > Services > Brede meta-analysis

Input

Brede Wiki CSV title: 


Column names Number Mean SD Events
Experimentals:
Controls:

Go to: Article | Data | CSV

Original data

First AuthorYearSubgroupNumber of PatientsNumber of ControlsPatient MeanPatient SDControl MeanControl SDPatient Age% Female PatientsAge of OnsetHam-D rating scaleAntidepressants %Mood stabilizers %Antipsychotics %Drug Free %ImagingMRI Field Strength (T)Slice Thickness (mm)PMID
Parashos IA1998723845.5615.4145.214.4255.462.538.5MRI1.559870413
Lavretsky H2005antidepressant exposure1120.50.0270.0030.0290.00367.463.636.417.7000100MRI1.51.416086609
Lavretsky H2005no antidepressant exposure3020.50.0260.0050.0290.00371.783.352.517.7000100MRI1.51.416086609
Chen HH20082726287.126.7614.463.011.7520.1000100MRI1.51.519108659

Interpreted data and analysis

Study Experimentals Controls Effects
Mean SD Events N Mean SD Events NSDpooled Effect SE CI Z P Weight WeightDSL
Parashos IA 1998 45.560000 15.410000 nan 72 45.200000 14.420000 nan 3815.078155 0.024 0.201 -0.369 0.417 0.118 0.906 24.871088 44.169% 6.668593 31.719%
Lavretsky H 2005 0.027000 0.003000 nan 11 0.029000 0.003000 nan 200.003000 -0.650 0.384 -1.402 0.103 -1.692 0.091 6.786811 12.053% 3.889629 18.501%
Lavretsky H 2005 0.026000 0.005000 nan 30 0.029000 0.003000 nan 200.004309 -0.685 0.295 -1.264 -0.107 -2.322 0.020 11.473325 20.376% 5.078513 24.156%
Chen HH 2008 28.000000 7.100000 nan 27 26.700000 6.000000 nan 266.583789 0.195 0.275 -0.345 0.734 0.706 0.480 13.177961 23.403% 5.386956 25.623%
Meta-analysis (fixed effect) 140 105 -0.162 0.133 -0.423 0.099 -1.215 0.224 100%
Meta-analysis (random effects, DSL) -0.228 0.218 -0.656 0.199 -1.047 0.295 100%
σa: 0.331284 Q: 7.289460 dof: 3.0 P-value: 0.063

Forest plot

-2 -1 0 1 2 Parashos IA 0.000000 Lavretsky H 1.000000 Lavretsky H 2.000000 Chen HH 3.000000 Meta-analysis (fixed effect) Meta-analysis (random effects)

Funnel plot

Effect size Standard error -0.20 -0.40 -0.60 -0.80 0.20 0.40 0.60 0.80 0.10 0.20 0.30 0.40

Warning

Column not matched "number_of_experimental_events". Column not matched "number_of_control_events".

Meta-analysis

This webservice will download a specified page from the Brede Wiki. The page should contain a comma-separated values (CSV) file with information for a meta-analysis. Study effect sizes and meta-analytic effect sizes will be computed.

The CSV file should provide information about the two groups: "experimentals" and "controls". The information you need to supply depends on whether your data is categorical (binary) or continuous:

You will usually need to specify the column names used for the data, but an automated guess will be performed if columns are not specified.

Symbols

M: mean, SD: standard deviation of data, SDpooled: Pooled standard deviation of data, N: number of data (subjects, etc.), MD: mean difference, SMD: standardized mean difference, CI: 95% confidence interval.

Examples

Acknowledgment

Matthew Kempton. Lundbeck Foundation Center for Integrated Molecular Brain Imaging (CIMBI)
Finn Årup Nielsen, CIMBI, DTU Informatics.