Brede meta-analysis


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Input

Brede Wiki CSV title: 


Column names Number Mean SD Events
Experimentals:
Controls:

Go to: Article | Data | CSV

Original data

First AuthorYearSubgroupNumber of PatientsNumber of ControlsPatient MeanPatient SDControl MeanControl SDPatient Age% Female PatientsAge of OnsetHam-D rating scaleAntidepressants %Mood stabilizers %Antipsychotics %Drug Free %ImagingMRI Field Strength (T)Slice Thickness (mm)PMID
Janssen J200428416.212.276.421.5964.04100.033.046125021MRI1.51.215576058
Lacerda AL200431345.891.096.421.8239.2677.427.9414.070100MRI1.51.514960287
Lavretsky H200743410.00860.00160.00970.000970.6776.749.617.7000100MRI1.51.417463189
Taylor WD20072261446.31.66.71.57066.445.40MRI1.5317335636
Chen HH200827267.92.27.61.714.463.011.7520.1000100MRI1.51.519108659

Interpreted data and analysis

Study Experimentals Controls Effects
Mean SD Events N Mean SD Events NSDpooled Effect SE CI Z P Weight WeightDSL
Janssen J 2004 6.210000 2.270000 nan 28 6.420000 1.590000 nan 411.893635 -0.110 0.245 -0.591 0.371 -0.447 0.655 16.612142 10.909% 8.916509 17.530%
Lacerda AL 2004 5.890000 1.090000 nan 31 6.420000 1.820000 nan 341.516848 -0.345 0.250 -0.836 0.145 -1.379 0.168 15.962762 10.482% 8.725974 17.155%
Lavretsky H 2007 0.008600 0.001600 nan 43 0.009700 0.000900 nan 410.001306 -0.834 0.228 -1.281 -0.387 -3.659 0.000 19.233045 12.630% 9.620155 18.913%
Taylor WD 2007 6.300000 1.600000 nan 226 6.700000 1.500000 nan 1441.561902 -0.256 0.107 -0.465 -0.046 -2.388 0.017 87.271899 57.308% 15.769630 31.003%
Chen HH 2008 7.900000 2.200000 nan 27 7.600000 1.700000 nan 261.970816 0.150 0.275 -0.389 0.689 0.545 0.586 13.205190 8.671% 7.831934 15.398%
Meta-analysis (fixed effect) 355 286 -0.287 0.081 -0.446 -0.128 -3.542 0.000 100%
Meta-analysis (random effects, DSL) -0.292 0.140 -0.567 -0.018 -2.085 0.037 100%
σa: 0.227935 Q: 8.946675 dof: 4.0 P-value: 0.062

Forest plot

-2 -1 0 1 2 Janssen J 0.000000 Lacerda AL 1.000000 Lavretsky H 2.000000 Taylor WD 3.000000 Chen HH 4.000000 Meta-analysis (fixed effect) Meta-analysis (random effects)

Funnel plot

Effect size Standard error -0.30 -0.60 -0.90 -1.20 0.30 0.60 0.90 1.20 0.08 0.16 0.24 0.32

Warning

Column not matched "number_of_experimental_events". Column not matched "number_of_control_events".

Meta-analysis

This webservice will download a specified page from the Brede Wiki. The page should contain a comma-separated values (CSV) file with information for a meta-analysis. Study effect sizes and meta-analytic effect sizes will be computed.

The CSV file should provide information about the two groups: "experimentals" and "controls". The information you need to supply depends on whether your data is categorical (binary) or continuous:

You will usually need to specify the column names used for the data, but an automated guess will be performed if columns are not specified.

Symbols

M: mean, SD: standard deviation of data, SDpooled: Pooled standard deviation of data, N: number of data (subjects, etc.), MD: mean difference, SMD: standardized mean difference, CI: 95% confidence interval.

Examples

Acknowledgment

Matthew Kempton. Lundbeck Foundation Center for Integrated Molecular Brain Imaging (CIMBI)
Finn Årup Nielsen, CIMBI, DTU Informatics.