Brede meta-analysis


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Input

Brede Wiki CSV title: 


Column names Number Mean SD Events
Experimentals:
Controls:

Go to: Article | Data | CSV

Original data

First AuthorYearSubgroupNumber of PatientsNumber of ControlsPatient MeanPatient SDControl MeanControl SDPatient Age% Female PatientsAge of OnsetHam-D rating scaleAntidepressants %Mood stabilizers %Antipsychotics %Drug Free %ImagingMRI Field Strength (T)Slice Thickness (mm)PMID
Janssen J200428416.412.366.681.864.04100.033.046125021MRI1.51.215576058
Lacerda AL200431346.521.216.981.8739.2677.427.9414.070100MRI1.51.514960287
Lavretsky H200743410.00860.00160.00960.00170.6776.749.617.7000100MRI1.51.417463189
Taylor WD20072261446.71.87.11.67066.445.40MRI1.5317335636
Chen HH200827268.62.181.714.463.011.7520.1000100MRI1.51.519108659

Interpreted data and analysis

Study Experimentals Controls Effects
Mean SD Events N Mean SD Events NSDpooled Effect SE CI Z P Weight WeightDSL
Janssen J 2004 6.410000 2.360000 nan 28 6.680000 1.800000 nan 412.044210 -0.131 0.245 -0.612 0.350 -0.532 0.595 16.601477 10.872% 8.847262 17.531%
Lacerda AL 2004 6.520000 1.210000 nan 31 6.980000 1.870000 nan 341.590252 -0.286 0.250 -0.775 0.204 -1.145 0.252 16.041395 10.505% 8.685650 17.211%
Lavretsky H 2007 0.008600 0.001600 nan 43 0.009600 0.001000 nan 410.001341 -0.739 0.226 -1.182 -0.296 -3.269 0.001 19.587045 12.827% 9.629471 19.081%
Taylor WD 2007 6.700000 1.800000 nan 226 7.100000 1.600000 nan 1441.725039 -0.231 0.107 -0.441 -0.022 -2.163 0.031 87.394519 57.232% 15.567576 30.848%
Chen HH 2008 8.600000 2.100000 nan 27 8.000000 1.700000 nan 261.914393 0.309 0.277 -0.233 0.851 1.117 0.264 13.076970 8.564% 7.736104 15.329%
Meta-analysis (fixed effect) 355 286 -0.245 0.081 -0.404 -0.086 -3.027 0.002 100%
Meta-analysis (random effects, DSL) -0.237 0.141 -0.513 0.039 -1.684 0.092 100%
σa: 0.229769 Q: 9.045028 dof: 4.0 P-value: 0.060

Forest plot

-2 -1 0 1 2 Janssen J 0.000000 Lacerda AL 1.000000 Lavretsky H 2.000000 Taylor WD 3.000000 Chen HH 4.000000 Meta-analysis (fixed effect) Meta-analysis (random effects)

Funnel plot

Effect size Standard error -0.20 -0.40 -0.60 -0.80 0.20 0.40 0.60 0.80 0.08 0.16 0.24 0.32

Warning

Column not matched "number_of_experimental_events". Column not matched "number_of_control_events".

Meta-analysis

This webservice will download a specified page from the Brede Wiki. The page should contain a comma-separated values (CSV) file with information for a meta-analysis. Study effect sizes and meta-analytic effect sizes will be computed.

The CSV file should provide information about the two groups: "experimentals" and "controls". The information you need to supply depends on whether your data is categorical (binary) or continuous:

You will usually need to specify the column names used for the data, but an automated guess will be performed if columns are not specified.

Symbols

M: mean, SD: standard deviation of data, SDpooled: Pooled standard deviation of data, N: number of data (subjects, etc.), MD: mean difference, SMD: standardized mean difference, CI: 95% confidence interval.

Examples

Acknowledgment

Matthew Kempton. Lundbeck Foundation Center for Integrated Molecular Brain Imaging (CIMBI)
Finn Årup Nielsen, CIMBI, DTU Informatics.