Brede meta-analysis


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Input

Brede Wiki CSV title: 


Column names Number Mean SD Events
Experimentals:
Controls:

Go to: Article | Data | CSV

Original data

First AuthorYearSubgroupNumber of PatientsNumber of ControlsPatients hyperintensityControls hyperintensityPatient Age% Female PatientsAge of OnsetHam-D rating scaleAntidepressants %Mood stabilizers %Antipsychotics %Drug Free %ImagingMRI Field Strength (T)Slice Thickness (mm)PMID
Coffey CE1990352220571.780.0MRI1.552301657
Brown FW1992281541640.3MRI171575251
Miller DS19941923346968.422MRI1.55NPD001
Kramer-Ginsberg E19994138393574.673.226MRI1710080561
Novaretti TM2001302029177176.7MRI11593278
Tupler LA2002115371133766.773.0MRI1.5512169341
Sassi RB2003183862142.888.930000100MRI1.51.514612223
Silverstone T200311195834.463.626.621.9MRI0.5512656939
Supprian T200410106548.960.00MRI1.5415465296
Iosifescu DV20068435351540.521.6MRI1.5316449707
Zanetti MV2008281020630.567.950145725MRI1.5318700214

Interpreted data and analysis

Study Experimentals Controls Effects
Mean SD Events N Mean SD Events NSDpooled Effect SE CI Z P Weight WeightDSL
Coffey CE 1990 nan nan nan 35 nan nan nan 22nan nan nan nan  nan nan nan 0.000000 0.000% 0.000000 0.000%
Brown FW 1992 nan nan nan 28 nan nan nan 154nan nan nan nan  nan nan nan 0.000000 0.000% 0.000000 0.000%
Miller DS 1994 nan nan nan 19 nan nan nan 23nan nan nan nan  nan nan nan 0.000000 0.000% 0.000000 0.000%
Kramer-Ginsberg E 1999 nan nan nan 41 nan nan nan 38nan nan nan nan  nan nan nan 0.000000 0.000% 0.000000 0.000%
Novaretti TM 2001 nan nan nan 30 nan nan nan 20nan nan nan nan  nan nan nan 0.000000 0.000% 0.000000 0.000%
Tupler LA 2002 nan nan nan 115 nan nan nan 37nan nan nan nan  nan nan nan 0.000000 0.000% 0.000000 0.000%
Sassi RB 2003 nan nan nan 18 nan nan nan 38nan nan nan nan  nan nan nan 0.000000 0.000% 0.000000 0.000%
Silverstone T 2003 nan nan nan 11 nan nan nan 19nan nan nan nan  nan nan nan 0.000000 0.000% 0.000000 0.000%
Supprian T 2004 nan nan nan 10 nan nan nan 10nan nan nan nan  nan nan nan 0.000000 0.000% 0.000000 0.000%
Iosifescu DV 2006 nan nan nan 84 nan nan nan 35nan nan nan nan  nan nan nan 0.000000 0.000% 0.000000 0.000%
Zanetti MV 2008 nan nan nan 28 nan nan nan 102nan nan nan nan  nan nan nan 0.000000 0.000% 0.000000 0.000%
Meta-analysis (fixed effect) 0 0 0.000 inf -inf inf 0.000 1.000 100%
Meta-analysis (random effects, DSL) nan inf nan  nan nan nan 100%
σa: 0.000000 Q: 0.000000 dof: -1.0 P-value: nan

Forest plot

Funnel plot

Effect size Standard error -0.50 -1.00 -1.50 -2.00 0.50 1.00 1.50 2.00 0.30 0.60 0.90 1.20

Warning

Column not matched "number_of_experimental_events". Column not matched "number_of_control_events". Column not matched "mean_experimentals". Column not matched "mean_controls". Column not matched "sd_experimentals". Column not matched "sd_controls". %d format: a number is required, not numpy.float64

Meta-analysis

This webservice will download a specified page from the Brede Wiki. The page should contain a comma-separated values (CSV) file with information for a meta-analysis. Study effect sizes and meta-analytic effect sizes will be computed.

The CSV file should provide information about the two groups: "experimentals" and "controls". The information you need to supply depends on whether your data is categorical (binary) or continuous:

You will usually need to specify the column names used for the data, but an automated guess will be performed if columns are not specified.

Symbols

M: mean, SD: standard deviation of data, SDpooled: Pooled standard deviation of data, N: number of data (subjects, etc.), MD: mean difference, SMD: standardized mean difference, CI: 95% confidence interval.

Examples

Acknowledgment

Matthew Kempton. Lundbeck Foundation Center for Integrated Molecular Brain Imaging (CIMBI)
Finn Årup Nielsen, CIMBI, DTU Informatics.