Brede meta-analysis


DTU Informatics >>> Neuroinformatics > Services > Brede meta-analysis

Input

Brede Wiki CSV title: 


Column names Number Mean SD Events
Experimentals:
Controls:

Go to: Article | Data | CSV

Original data

First AuthorYearSubgroupNumber of PatientsNumber of ControlsPatient MeanPatient SDControl MeanControl SDPatient Age% Female PatientsAge of OnsetHam-D rating scaleAntidepressants %Mood stabilizers %Antipsychotics %Drug Free %ImagingMRI Field Strength (T)Slice Thickness (mm)PMID
Husain MM (B)199141443.71.24.91.455.3MRI1.551763144
Lenze EJ (B)199924243.930.643.910.6253100.0MRI1.2510588417
Lacerda AL200325482.330.82.40.8241.216.029.4410.91000100MRI1.5514623065
Matsuo K200827263.60.613.790.5314.463.011.75000100MRI1.51.518439110
Pan CC2009170833.630.783.690.7169.465.9MRI1.5319235787
Pizzagalli DA200926315364697536971743.1757.729.3915.98000100MRI1.51.3319411368

Interpreted data and analysis

Study Experimentals Controls Effects
Mean SD Events N Mean SD Events NSDpooled Effect SE CI Z P Weight WeightDSL
Husain MM (B) 1991 3.700000 1.200000 nan 41 4.900000 1.400000 nan 441.307439 -0.910 0.229 -1.357 -0.462 -3.980 0.000 19.149782 14.674% 8.052888 17.176%
Lenze EJ (B) 1999 3.930000 0.640000 nan 24 3.910000 0.620000 nan 240.630079 0.031 0.289 -0.535 0.597 0.108 0.914 11.998407 9.194% 6.439004 13.734%
Lacerda AL 2003 2.330000 0.800000 nan 25 2.400000 0.820000 nan 480.813294 -0.085 0.247 -0.569 0.398 -0.345 0.730 16.424181 12.585% 7.527571 16.056%
Matsuo K 2008 3.600000 0.610000 nan 27 3.790000 0.530000 nan 260.572184 -0.327 0.277 -0.870 0.215 -1.182 0.237 13.056641 10.005% 6.731807 14.359%
Pan CC 2009 3.630000 0.780000 nan 170 3.690000 0.710000 nan 830.757843 -0.079 0.134 -0.341 0.184 -0.589 0.556 55.731872 42.706% 11.123200 23.725%
Pizzagalli DA 2009 5364.000000 697.000000 nan 26 5369.000000 717.000000 nan 31707.979134 -0.007 0.266 -0.528 0.514 -0.026 0.979 14.140259 10.835% 7.008730 14.949%
Meta-analysis (fixed effect) 313 256 -0.209 0.088 -0.380 -0.037 -2.382 0.017 100%
Meta-analysis (random effects, DSL) -0.232 0.146 -0.519 0.054 -1.591 0.112 100%
σa: 0.268252 Q: 12.043472 dof: 5.0 P-value: 0.034

Forest plot

-2 -1 0 1 2 Husain MM (B) 0.000000 Lenze EJ (B) 1.000000 Lacerda AL 2.000000 Matsuo K 3.000000 Pan CC 4.000000 Pizzagalli DA 5.000000 Meta-analysis (fixed effect) Meta-analysis (random effects)

Funnel plot

Effect size Standard error -0.30 -0.60 -0.90 -1.20 0.30 0.60 0.90 1.20 0.08 0.16 0.24 0.32

Warning

Column not matched "number_of_experimental_events". Column not matched "number_of_control_events".

Meta-analysis

This webservice will download a specified page from the Brede Wiki. The page should contain a comma-separated values (CSV) file with information for a meta-analysis. Study effect sizes and meta-analytic effect sizes will be computed.

The CSV file should provide information about the two groups: "experimentals" and "controls". The information you need to supply depends on whether your data is categorical (binary) or continuous:

You will usually need to specify the column names used for the data, but an automated guess will be performed if columns are not specified.

Symbols

M: mean, SD: standard deviation of data, SDpooled: Pooled standard deviation of data, N: number of data (subjects, etc.), MD: mean difference, SMD: standardized mean difference, CI: 95% confidence interval.

Examples

Acknowledgment

Matthew Kempton. Lundbeck Foundation Center for Integrated Molecular Brain Imaging (CIMBI)
Finn Årup Nielsen, CIMBI, DTU Informatics.