Brede meta-analysis


DTU Informatics >>> Neuroinformatics > Services > Brede meta-analysis

Input

Brede Wiki CSV title: 


Column names Number Mean SD Events
Experimentals:
Controls:

Go to: Article | Data | CSV

Original data

First AuthorYearSubgroupNumber of PatientsNumber of ControlsPatient MeanPatient SDControl MeanControl SDPatient Age% Female PatientsAge of OnsetHam-D rating scaleAntidepressants %Mood stabilizers %Antipsychotics %Drug Free %ImagingMRI Field Strength (T)Slice Thickness (mm)PMID
Pantel J1997191346.547.0347.396.972.478.964.226.7MRI1.51.259089060
Bremner JD200016161793141701822717914337.5100000MRI1.5310618023
McIntosh AM200192973375549979352647843.5655.6MRI11.8811200955
Caetano SC2004313171.398.2969.99.1639.277.427.911.8000100MRI1.51.515598548
Vythilingam M200438331539615861666019354160.5039MRI1.51.515231442

Interpreted data and analysis

Study Experimentals Controls Effects
Mean SD Events N Mean SD Events NSDpooled Effect SE CI Z P Weight WeightDSL
Pantel J 1997 46.540000 7.030000 nan 19 47.390000 6.900000 nan 136.978291 -0.119 0.360 -0.825 0.587 -0.330 0.742 7.703812 14.264% 3.874252 17.783%
Bremner JD 2000 17931.000000 4170.000000 nan 16 18227.000000 1791.000000 nan 163209.094966 -0.090 0.354 -0.783 0.603 -0.254 0.799 7.990791 14.796% 3.945512 18.110%
McIntosh AM 2001 73375.000000 5499.000000 nan 9 79352.000000 6478.000000 nan 296273.660902 -0.933 0.398 -1.713 -0.153 -2.344 0.019 6.314521 11.692% 3.488287 16.011%
Caetano SC 2004 71.390000 8.290000 nan 31 69.900000 9.160000 nan 318.735837 0.168 0.254 -0.330 0.667 0.662 0.508 15.441534 28.591% 5.179498 23.774%
Vythilingam M 2004 15396.000000 1586.000000 nan 38 16660.000000 1935.000000 nan 331756.498708 -0.712 0.246 -1.193 -0.230 -2.896 0.004 16.557365 30.657% 5.299288 24.323%
Meta-analysis (fixed effect) 113 122 -0.309 0.136 -0.576 -0.043 -2.273 0.023 100%
Meta-analysis (random effects, DSL) -0.320 0.214 -0.740 0.100 -1.493 0.135 100%
σa: 0.358202 Q: 9.324498 dof: 4.0 P-value: 0.053

Forest plot

-2 -1 0 1 2 Pantel J 0.000000 Bremner JD 1.000000 McIntosh AM 2.000000 Caetano SC 3.000000 Vythilingam M 4.000000 Meta-analysis (fixed effect) Meta-analysis (random effects)

Funnel plot

Effect size Standard error -0.30 -0.60 -0.90 -1.20 0.30 0.60 0.90 1.20 0.10 0.20 0.30 0.40

Warning

Column not matched "number_of_experimental_events". Column not matched "number_of_control_events".

Meta-analysis

This webservice will download a specified page from the Brede Wiki. The page should contain a comma-separated values (CSV) file with information for a meta-analysis. Study effect sizes and meta-analytic effect sizes will be computed.

The CSV file should provide information about the two groups: "experimentals" and "controls". The information you need to supply depends on whether your data is categorical (binary) or continuous:

You will usually need to specify the column names used for the data, but an automated guess will be performed if columns are not specified.

Symbols

M: mean, SD: standard deviation of data, SDpooled: Pooled standard deviation of data, N: number of data (subjects, etc.), MD: mean difference, SMD: standardized mean difference, CI: 95% confidence interval.

Examples

Acknowledgment

Matthew Kempton. Lundbeck Foundation Center for Integrated Molecular Brain Imaging (CIMBI)
Finn Årup Nielsen, CIMBI, DTU Informatics.