Brede meta-analysis


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Input

Brede Wiki CSV title: 


Column names Number Mean SD Events
Experimentals:
Controls:

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Original data

First authorYearTraitGroupMean patientsSE patientsSD patientsNumber of patientsMean controlsSE controlsSD ControlsNumber of controlsMean patient ageSD patient ageMean control ageSD control ageNotesPMIDTitle
Fujii2000TPQ novelty seeking12.363.026713.713.156956.2212.2865.934.1710686542Cross-cultural traits for personality of patients with Parkinson's disease in Japan
Jacobs2001TPQ novelty seeking14.44.712214.8512244.9444.54.611227136Personality traits in young patients with Parkinson's disease
Kaasinen2001TCI novelty seeking13.10.765.93578975376115.60.895.97030149994562.17.959.88.711687621Personality traits and brain dopaminergic function in Parkinson's disease
Tomer2004TPQ novelty seekingLeft onset12.53.61814.94.71766.79.163.810.1Control group overlap15201352Novelty seeking and harm avoidance in Parkinson's disease: effects of asymmetric dopamine deficiency
Tomer2004TPQ novelty seekingRight onset11.52.92214.94.71762.7963.810.1Control group overlap15201352Novelty seeking and harm avoidance in Parkinson's disease: effects of asymmetric dopamine deficiency
McNamara2008TCI novelty seeking17.66.13415.14.81770.611.165.67.417562520Alterations of the sense of self and personality in Parkinson's disease
Bodi2009TCI novelty seekingNever-medicated174.22620.83.22044.85.245.38.5Control group overlap19416950Reward-learning and the novelty-seeking personality: a between- and within-subjects study of the effects of dopamine agonists on young Parkinson's patients
Bodi2009TCI novelty seekingRecently medicated257.42220.83.22045.38.245.38.5Control group overlap19416950Reward-learning and the novelty-seeking personality: a between- and within-subjects study of the effects of dopamine agonists on young Parkinson's patients
Fassino2010TCI novelty seekingDeep brain stimulation16.735.022216.185.572264.096.2765.56.89Control group overlap20118442Novelty-seeking in Parkinson's disease after deep brain stimulation of the subthalamic nucleus: a case-control study
Fassino2010TCI novelty seekingNo deep brain stimulation13.364.022216.185.572268.097.7365.56.89Control group overlap20118442Novelty-seeking in Parkinson's disease after deep brain stimulation of the subthalamic nucleus: a case-control study

Interpreted data and analysis

Study Experimentals Controls Effects
Mean SD Events N Mean SD Events NSDpooled Effect SE CI Z P Weight WeightDSL
Fujii 2000 12.360000 3.020000 nan 67 13.710000 3.150000 nan 693.086654 -0.435 0.174 -0.775 -0.095 -2.505 0.012 33.184798 17.566% 6.129553 12.643%
Jacobs 2001 14.400000 4.700000 nan 122 14.800000 5.000000 nan 1224.852319 -0.082 0.128 -0.333 0.169 -0.642 0.521 60.947705 32.263% 6.692667 13.804%
Kaasinen 2001 13.100000 5.935790 nan 61 15.600000 5.970301 nan 455.950415 -0.417 0.199 -0.806 -0.028 -2.100 0.036 25.336997 13.412% 5.797850 11.958%
Tomer 2004 12.500000 3.600000 nan 18 14.900000 4.700000 nan 174.169732 -0.562 0.346 -1.240 0.115 -1.627 0.104 8.370256 4.431% 3.960703 8.169%
Tomer 2004 11.500000 2.900000 nan 22 14.900000 4.700000 nan 173.784927 -0.880 0.340 -1.546 -0.214 -2.591 0.010 8.671434 4.590% 4.026885 8.306%
McNamara 2008 17.600000 6.100000 nan 34 15.100000 4.800000 nan 175.708157 0.431 0.300 -0.157 1.020 1.436 0.151 11.085113 5.868% 4.479869 9.240%
Bodi 2009 17.000000 4.200000 nan 26 20.800000 3.200000 nan 203.800598 -0.983 0.316 -1.602 -0.363 -3.108 0.002 10.005842 5.297% 4.292741 8.854%
Bodi 2009 25.000000 7.400000 nan 22 20.800000 3.200000 nan 205.797672 0.711 0.320 0.085 1.337 2.224 0.026 9.795166 5.185% 4.253492 8.773%
Fassino 2010 16.730000 5.020000 nan 22 16.180000 5.570000 nan 225.302136 0.102 0.302 -0.490 0.693 0.338 0.736 10.984350 5.815% 4.463322 9.206%
Fassino 2010 13.360000 4.020000 nan 22 16.180000 5.570000 nan 224.857227 -0.570 0.308 -1.174 0.034 -1.850 0.064 10.530043 5.574% 4.386424 9.047%
Meta-analysis (fixed effect) 416 371 -0.240 0.073 -0.383 -0.097 -3.297 0.001 100%
Meta-analysis (random effects, DSL) -0.262 0.144 -0.544 0.019 -1.826 0.068 100%
σa: 0.364705 Q: 29.794480 dof: 9.0 P-value: 0.000

Forest plot

-2 -1 0 1 2 Fujii 0.000000 Jacobs 1.000000 Kaasinen 2.000000 Tomer 3.000000 Tomer 4.000000 McNamara 5.000000 Bodi 6.000000 Bodi 7.000000 Fassino 8.000000 Fassino 9.000000 Meta-analysis (fixed effect) Meta-analysis (random effects)

Funnel plot

Effect size Standard error -0.30 -0.60 -0.90 -1.20 0.30 0.60 0.90 1.20 0.10 0.20 0.30 0.40

Warning

Column not matched "number_of_experimental_events". Column not matched "number_of_control_events".

Meta-analysis

This webservice will download a specified page from the Brede Wiki. The page should contain a comma-separated values (CSV) file with information for a meta-analysis. Study effect sizes and meta-analytic effect sizes will be computed.

The CSV file should provide information about the two groups: "experimentals" and "controls". The information you need to supply depends on whether your data is categorical (binary) or continuous:

You will usually need to specify the column names used for the data, but an automated guess will be performed if columns are not specified.

Symbols

M: mean, SD: standard deviation of data, SDpooled: Pooled standard deviation of data, N: number of data (subjects, etc.), MD: mean difference, SMD: standardized mean difference, CI: 95% confidence interval.

Examples

Acknowledgment

Matthew Kempton. Lundbeck Foundation Center for Integrated Molecular Brain Imaging (CIMBI)
Finn Årup Nielsen, CIMBI, DTU Informatics.