WOROI: 218 - Medial temporal lobe
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WOROI: 218 - Medial temporal lobe

An area in the temporal lobe consisting of the hippocampus, parahippocampal gyrus and perirhinal and entorhinal cortices. It is not to be confused with medial temporal gyrus (aka middle temporal gyrus).

Abbreviation: MTL

External databases


Temporal lobe
Parahippocampal gyrus
Entorhinal cortex
Mesial anterior temporal lobe
Perirhinal cortex
Left medial temporal lobe
Right medial temporal lobe
Brodmann area 28
Brodmann area 34
Brodmann area 35
Brodmann area 36
Piriform cortex

Talairach coordinates

  x     y     z   Lobar anatomy WOBIB WOEXP
22 -7 -23 Right anterior medial temporal lobe encompassing perirhinal cortex 139 427
39 -18 -17 Right medial temporal lobe 167 511
-39 -16 -19 Left medial temporal lobe 167 511


  x     y     z   Description
-39 -16 -19 Mean coordinate in left hemisphere
30 -13 -20 Mean coordinate in right hemisphere
33 -14 -20 Mean coordinate with ignored left/right
22 -18 -23 Minimum coordinate with ignored left/right
39 -7 -17 Maximum coordinate with ignored left/right
10 6 3 Standard deviation with ignored left/right
corner cube of WOROI: 218 - Medial temporal lobe

Text contexts

By adapting functional magnetic resonance imaging scanning parameters to maximize sensitivity to medial temporal lobe activity, we demonstrate that left perirhinal and hippocampal responses during word list encoding are greater for subsequently recalled than forgotten wordsB. A. Strange; L. J. Otten; Oliver Josephs; Michael D. Rugg; Raymond J. Dolan. Dissociable human perirhinal, hippocampal, and parahippocampal roles during verbal encoding. Journal of Neuroscience 22(2):523-528, 2002. PMID: 11784798. FMRIDCID: . WOBIB: 142.
Functional magnetic resonance imaging (fMRI) was used to examine whether (1) verbal associative encoding activates the medial temporal lobes (MTL) and related regions more than non-associative encoding, (2) verbal associative novelty is related to enhanced MTL activation, and (3) verbal item novelty is related to enhanced MTL activation and, if so, whether these activations are in different or overlapping sitesNicola M. Hunkin; Andrew R. Mayes; Lloyd J. Gregory; Amanda K. Nicholas; Julia A. Nunn; Michael J. Brammer; Edward T. Bullmore; Steven C. R. Williams. Novelty-related activation within the medial temporal lobes. Neuropsychologia 40(8):1456-1464, 2002. PMID: 11931949. FMRIDCID: . WOBIB: 143.
Together, our findings suggest that new semantic associations can be formed and retrieved by way of the medial temporal lobe without awareness of the associations or its components at encoding or any awareness that one is remembering at retrievalKatharina Henke; Christian R. A. Mondadori; Valerie Treyer; Roger M. Nitsch; Alfred Buck; Christoph Hock. Nonconscious formation and reactivation of semantic associations by way of the medial temporal lobe. Neuropsychologia 41(8):863-876, 2003. PMID: 12667523. FMRIDCID: . WOBIB: 152.
The medial temporal lobe (MTL) has been associated with declarative learning of flexible relational rules and the basal ganglia with implicit learning of stimulus-response mappingsMichael Rose; Hilde Haider; Cornelius Weiller; Christian Buchel. The Role of Medial Temporal Lobe Structures in Implicit Learning: An Event-Related fMRI Study. Neuron 36(6):1221-1231, 2002. PMID: 12495634. DOI: 10.1016/S0896-6273(02)01105-4. FMRIDCID: . WOBIB: 167.
Retrieval of old items was associated with increased blood flow in the left medial temporal lobe and with a brief late positive ERP componentEmrah Düzel; Roberto Cabeza; Terence W. Picton; Andrew P. Yonelinas; Henning Scheich; Hans-Jochen Heinze; Endel Tulving. Task-related and item-related brain processes of memory retrieval. Proceedings of the National Academy of Science of the United States of America 96(4):1794-1799, 1999. PMID: 9990104. FMRIDCID: . WOBIB: 181.

Text count

Bib -> Asymmetry | Author | ICA | NMF | Novelty | Statistics | SVD | Title | WOBIB ]
Roi -> Alphabetic | Hammers | Tzourio-Mazoyer | Svarer | Top | Functional areas | Brodmann areas ]
[ Brede Database ]
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