WOEXT: 414 - Second-generation histamine H1 antagonist
 
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WOEXT: 414. Second-generation histamine H1 antagonist.

MeSH UID: D039563.

ParentsSiblingsChildren
Histamine H1 Antagonist
Ebastine
(+)-Chlorpheniramine

Experiments:

No experiments

Child experiments:

  1. Binding potential of doxepin after ebastine compared to after chlorpheniramine. Binding potential of doxepin on histamine H1 receptor after administering of 10 mg of ebatine versus binding potential after administring of 2 mg of (+)-chlorpheniramine. WOEXP: 392.
    M. Tagawa; M. Kano; N. Okamura; M. Higuchi; M. Matsuda; Y. Mizuki; H. Arai; R. Iwata; T. Fujii; S. Komemushi; T. Ido; M. Itoh; H. Sasaki; T. Watanabe; K. Yanai. Neuroimaging of histamine H1-receptor occupancy in human brain by positron emission tomography (PET): a comparative study of ebastine, a second-generation antihistamine, and (+)-chlorpheniramine, a classical antihistamine. British Journal of Clinical Pharmacology 52(5):501-509, 2001. PMID: 11736858. WOBIB: 127.
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