5-HTR1A, 5-HTR2A, 5-HTR6, TPH1 and TPH2 polymorphisms and major depression
|5-HTR1A, 5-HTR2A, 5-HTR6, TPH1 and TPH2 polymorphisms and major depression|
|Authors:||Ari Illi, Eija Setälä-Soikkeli, Merja Viikki, Outi Poutanen, Heini Huhtala, Nina Mononen, Terho Lehtimäki, Esa Leinonen, Olli Kampman|
|Citation:||NeuroReport 20 (12): 1125-1128. 2009 August|
|Web:||Bing Google Yahoo! — Google PDF|
|Article:||BASE Google Scholar PubMed|
|Restricted:||DTU Digital Library|
|Format:||BibTeX Template from PMID|
|Extract:||Talairach coordinates from linked PDF: CSV-formated wiki-formated|
5-HTR1A, 5-HTR2A, 5-HTR6, TPH1 and TPH2 polymorphisms and major depression reports a genetics study on major depressive disorder with serotonin system polymorphisms, r6295, rs6313, rs6311, rs7997012, rs1805054, rs1800532 and rs1386494. This is both an ordinary association study as well as a treatment response study.
The study find no association between patients and controls, or between remission and nonremission groups, or between responder and nonresponder groups.
|Subject group #1 (help)|
|Treated major depressive disorder patients|
|Subjects/♂/♀:||86 / /|
|Age:||40.7 ±14.0 (–)|
|Approval:||Local ethics committee|
Group 1 of 86 treated major depressive disorder patients were included in the study. The Finnish group had a mean age of 40.7. The study on the human subjects was approved by the Local ethics committee.