Allelic variants of the tryptophan hydroxylase (A218C) and serotonin 1B receptor (A-161T) and personality traits

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Allelic variants of the tryptophan hydroxylase (A218C) and serotonin 1B receptor (A-161T) and personality traits
Authors: Shih-Jen Tsai, Ying-Chieh Wang, Jen-Yeu Chen, Chen-Jee Hong
Citation: Neuropsychobiology 48 (2): 68-61. 2003
Database(s): PubMed (PMID/14504413)
DOI: 10.1159/000072879.
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Allelic variants of the tryptophan hydroxylase (A218C) and serotonin 1B receptor (A-161T) and personality traits reports a personality genetics study on TPH1 A218C and HTR1B A-161T polymorphism and personality traits assessed with the Tridimensional Personality Questionnaire.

[edit] Results

Gene Polymorphism Genotype Inventory Trait Mean Std Subjects Recruitment PMID
TPH1 A218C A/A TPQ Novelty seeking 15.5 4.4 37 Taiwanese medical staff and students 14504413
TPH1 A218C A/A TPQ Reward dependence 17.2 3.5 37 Taiwanese medical staff and students 14504413
TPH1 A218C A/A TPQ Harm avoidance 14.3 7.9 37 Taiwanese medical staff and students 14504413
TPH1 A218C A/A TPQ Anticipatory worry 4.1 2.7 37 Taiwanese medical staff and students 14504413
TPH1 A218C A/A TPQ Fear of uncertainty 4.1 2.1 37 Taiwanese medical staff and students 14504413
TPH1 A218C A/A TPQ Shyness with strangers 3.0 2.3 37 Taiwanese medical staff and students 14504413
TPH1 A218C A/A TPQ Fatigability and asthenia 3.1 2.5 37 Taiwanese medical staff and students 14504413
TPH1 A218C A/C TPQ Novelty seeking 15.6 5.0 110 Taiwanese medical staff and students 14504413
TPH1 A218C A/C TPQ Reward dependence 18.4 3.8 110 Taiwanese medical staff and students 14504413
TPH1 A218C A/C TPQ Harm avoidance 15.4 6.8 110 Taiwanese medical staff and students 14504413
TPH1 A218C A/C TPQ Anticipatory worry 4.1 2.5 110 Taiwanese medical staff and students 14504413
TPH1 A218C A/C TPQ Fear of uncertainty 4.5 1.7 110 Taiwanese medical staff and students 14504413
TPH1 A218C A/C TPQ Shyness with strangers 3.3 2.2 110 Taiwanese medical staff and students 14504413
TPH1 A218C A/C TPQ Fatigability and asthenia 3.5 2.5 110 Taiwanese medical staff and students 14504413
TPH1 A218C C/C TPQ Novelty seeking 16.8 4.4 62 Taiwanese medical staff and students 14504413
TPH1 A218C C/C TPQ Reward dependence 18.2 4.2 62 Taiwanese medical staff and students 14504413
TPH1 A218C C/C TPQ Harm avoidance 14.5 6.9 62 Taiwanese medical staff and students 14504413
TPH1 A218C C/C TPQ Anticipatory worry 3.7 2.5 62 Taiwanese medical staff and students 14504413
TPH1 A218C C/C TPQ Fear of uncertainty 4.0 1.9 62 Taiwanese medical staff and students 14504413
TPH1 A218C C/C TPQ Shyness with strangers 3.4 2.1 62 Taiwanese medical staff and students 14504413
TPH1 A218C C/C TPQ Fatigability and asthenia 3.3 2.6 62 Taiwanese medical staff and students 14504413
HTR1B A-161T A/A TPQ Novelty seeking 16.0 4.7 164 Taiwanese medical staff and students 14504413
HTR1B A-161T A/A TPQ Reward dependence 17.9 4.1 164 Taiwanese medical staff and students 14504413
HTR1B A-161T A/A TPQ Harm avoidance 14.7 6.9 164 Taiwanese medical staff and students 14504413
HTR1B A-161T A/A TPQ Anticipatory worry 4.0 2.5 164 Taiwanese medical staff and students 14504413
HTR1B A-161T A/A TPQ Fear of uncertainty 4.3 1.9 164 Taiwanese medical staff and students 14504413
HTR1B A-161T A/A TPQ Shyness with strangers 3.2 2.2 164 Taiwanese medical staff and students 14504413
HTR1B A-161T A/A TPQ Fatigability and asthenia 3.3 2.5 164 Taiwanese medical staff and students 14504413
HTR1B A-161T A/T TPQ Novelty seeking 15.6 4.9 44 Taiwanese medical staff and students 14504413
HTR1B A-161T A/T TPQ Reward dependence 18.7 3.2 44 Taiwanese medical staff and students 14504413
HTR1B A-161T A/T TPQ Harm avoidance 15.8 7.5 44 Taiwanese medical staff and students 14504413
HTR1B A-161T A/T TPQ Anticipatory worry 4.3 2.8 44 Taiwanese medical staff and students 14504413
HTR1B A-161T A/T TPQ Fear of uncertainty 4.3 1.7 44 Taiwanese medical staff and students 14504413
HTR1B A-161T A/T TPQ Shyness with strangers 3.6 2.2 44 Taiwanese medical staff and students 14504413
HTR1B A-161T A/T TPQ Fatigability and asthenia 3.7 2.8 44 Taiwanese medical staff and students 14504413
HTR1B A-161T T/T TPQ Novelty seeking 12 0 1 Taiwanese medical staff and students 14504413
HTR1B A-161T T/T TPQ Reward dependence 17 0 1 Taiwanese medical staff and students 14504413
HTR1B A-161T T/T TPQ Harm avoidance 10 0 1 Taiwanese medical staff and students 14504413
HTR1B A-161T T/T TPQ Anticipatory worry 0 0 1 Taiwanese medical staff and students 14504413
HTR1B A-161T T/T TPQ Fear of uncertainty 4 0 1 Taiwanese medical staff and students 14504413
HTR1B A-161T T/T TPQ Shyness with strangers 4 0 1 Taiwanese medical staff and students 14504413
HTR1B A-161T T/T TPQ Fatigability and asthenia 2 0 1 Taiwanese medical staff and students 14504413


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