An association study of a functional polymorphism of the serotonin transporter gene with personality and psychiatric symptoms

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An association study of a functional polymorphism of the serotonin transporter gene with personality and psychiatric symptoms
Authors: Anthony F. Jorm, A. S. Henderson, P. A. Jacomb, H. Christensen, A. E. Korten, B. Rodgers, X. Tan, S. Easteal
Citation: Molecular Psychiatry 3 (5): 449-441. 1998 September
Database(s): PubMed (PMID/9774781)
DOI: 10.1038/sj.mp.4000424.
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An association study of a functional polymorphism of the serotonin transporter gene with personality and psychiatric symptoms reports a personality genetics study on the 5-HTTLPR polymorphims.

The results are also listed in the paper Association of dopamine-β-hydroxylase and androgen receptor gene polymorphisms with Eysenck's P and other personality traits.


[edit] Results

Gene Polymorphism Genotype Inventory Trait Mean Std Subjects Recruitment PMID
SLC6A4 5-HTTLPR long/long EPQ-R Neuroticism 4.42 3.33 254 Australian Caucasians 9774781
SLC6A4 5-HTTLPR long/short EPQ-R Neuroticism 4.49 3.27 350 Australian Caucasians 9774781
SLC6A4 5-HTTLPR short/short EPQ-R Neuroticism 4.36 3.50 155 Australian Caucasians 9774781
SLC6A4 5-HTTLPR long/long EPQ-R Extraversion 7.12 3.39 254 Australian Caucasians 9774781
SLC6A4 5-HTTLPR long/short EPQ-R Extraversion 7.15 3.57 350 Australian Caucasians 9774781
SLC6A4 5-HTTLPR short/short EPQ-R Extraversion 7.52 3.35 155 Australian Caucasians 9774781
SLC6A4 5-HTTLPR long/long EPQ-R Psychoticism 1.99 1.62 254 Australian Caucasians 9774781
SLC6A4 5-HTTLPR long/short EPQ-R Psychoticism 2.19 1.60 350 Australian Caucasians 9774781
SLC6A4 5-HTTLPR short/short EPQ-R Psychoticism 1.89 1.60 155 Australian Caucasians 9774781
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