An association study of the 5-HTTLPR and COMT genes polymorphisms and personality traits

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An association study of the 5-HTTLPR and COMT genes polymorphisms and personality traits
Authors: Jee-Hyun Ha, Byung-Joo Ham, Sung-Gon Ryu, Tae-Yeon Hwang, Jong-Gook Lee, Yu-Sang Lee, Jung-Sik Lee, Dae Yeob Kang, Ihn-Geun Choi, Min Soo Lee
Citation: Korean Journal of Biological Psychiatry 11 (2): 88-93. 2004 November
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Link(s): http://journal.biolpsychiatry.or.kr/asp/pdfdown.asp?pn=0092004010
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An association study of the 5-HTTLPR and COMT genes polymorphisms and personality traits reports a personality genetics study with the SLC6A4 5-HTTLPR and COMT val158met genetic polymorphisms and personality traits assessed with the Temperament and Character Inventory.

The main body of the text is written in Korean.

A related study is An association study of catechol-O-methyltransferase and monoamine oxidase A polymorphisms and personality traits in Koreans.

[edit] Subjects

Subject group #1 (help)
Healthy Korean students
Subjects/♂/♀: 116 / 70 / 46
Age: 22.37 ±1.55 (–)
Nationality: Korean
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Group 1 of 116 healthy Korean students with 70 males and 46 females were included in the study. The Korean group had a mean age of 22.37.

The subjects were healthy adults.

[edit] Results

Gene Polymorphism Genotype Inventory Trait Mean Std Subjects Recruitment PMID
SLC6A4 5-HTTLPR long/long TCI Novelty seeking 15.25 4.64 4 Healthy Korean students Ha 2004
SLC6A4 5-HTTLPR long/short TCI Novelty seeking 17.64 6.03 34 Healthy Korean students Ha 2004
SLC6A4 5-HTTLPR short/short TCI Novelty seeking 18.29 5.42 78 Healthy Korean students Ha 2004
SLC6A4 5-HTTLPR long/long TCI Harm avoidance 18.00 4.54 4 Healthy Korean students Ha 2004
SLC6A4 5-HTTLPR long/short TCI Harm avoidance 16.44 7.05 34 Healthy Korean students Ha 2004
SLC6A4 5-HTTLPR short/short TCI Harm avoidance 15.37 6.61 78 Healthy Korean students Ha 2004
SLC6A4 5-HTTLPR long/long TCI Reward dependence 15.75 3.86 4 Healthy Korean students Ha 2004
SLC6A4 5-HTTLPR long/short TCI Reward dependence 14.85 4.00 34 Healthy Korean students Ha 2004
SLC6A4 5-HTTLPR short/short TCI Reward dependence 15.39 3.74 78 Healthy Korean students Ha 2004
SLC6A4 5-HTTLPR long/long TCI Persistence 4.25 2.36 4 Healthy Korean students Ha 2004
SLC6A4 5-HTTLPR long/short TCI Persistence 4.97 1.89 34 Healthy Korean students Ha 2004
SLC6A4 5-HTTLPR short/short TCI Persistence 4.79 2.02 78 Healthy Korean students Ha 2004
SLC6A4 5-HTTLPR long/long TCI Self-directedness 22.50 8.16 4 Healthy Korean students Ha 2004
SLC6A4 5-HTTLPR long/short TCI Self-directedness 26.61 8.15 34 Healthy Korean students Ha 2004
SLC6A4 5-HTTLPR short/short TCI Self-directedness 25.25 6.65 78 Healthy Korean students Ha 2004
SLC6A4 5-HTTLPR long/long TCI Cooperativeness 27.00 7.43 4 Healthy Korean students Ha 2004
SLC6A4 5-HTTLPR long/short TCI Cooperativeness 28.79 7.27 34 Healthy Korean students Ha 2004
SLC6A4 5-HTTLPR short/short TCI Cooperativeness 29.55 6.34 78 Healthy Korean students Ha 2004
SLC6A4 5-HTTLPR long/long TCI Self-transcendence 9.75 4.64 4 Healthy Korean students Ha 2004
SLC6A4 5-HTTLPR long/short TCI Self-transcendence 12.67 5.20 34 Healthy Korean students Ha 2004
SLC6A4 5-HTTLPR short/short TCI Self-transcendence 14.79 6.61 78 Healthy Korean students Ha 2004
COMT met158val met/met TCI Novelty seeking 14.71 5.08 7 Healthy Korean students Ha 2004
COMT met158val met/val TCI Novelty seeking 18.89 4.27 38 Healthy Korean students Ha 2004
COMT met158val val/val TCI Novelty seeking 17.83 6.07 68 Healthy Korean students Ha 2004
COMT met158val met/met TCI Harm avoidance 19.28 10.17 7 Healthy Korean students Ha 2004
COMT met158val met/val TCI Harm avoidance 14.18 5.77 38 Healthy Korean students Ha 2004
COMT met158val val/val TCI Harm avoidance 16.17 6.69 68 Healthy Korean students Ha 2004
COMT met158val met/met TCI Reward dependence 16.85 5.11 7 Healthy Korean students Ha 2004
COMT met158val met/val TCI Reward dependence 15.42 3.34 38 Healthy Korean students Ha 2004
COMT met158val val/val TCI Reward dependence 15.10 3.86 68 Healthy Korean students Ha 2004
COMT met158val met/met TCI Persistence 5.42 1.39 7 Healthy Korean students Ha 2004
COMT met158val met/val TCI Persistence 4.73 1.68 38 Healthy Korean students Ha 2004
COMT met158val val/val TCI Persistence 4.80 2.21 68 Healthy Korean students Ha 2004
COMT met158val met/met TCI Self-directedness 23.85 10.99 7 Healthy Korean students Ha 2004
COMT met158val met/val TCI Self-directedness 26.10 6.71 38 Healthy Korean students Ha 2004
COMT met158val val/val TCI Self-directedness 25.41 6.93 68 Healthy Korean students Ha 2004
COMT met158val met/met TCI Cooperativeness 32.71 7.36 7 Healthy Korean students Ha 2004
COMT met158val met/val TCI Cooperativeness 30.36 5.19 38 Healthy Korean students Ha 2004
COMT met158val val/val TCI Cooperativeness 28.29 7.13 68 Healthy Korean students Ha 2004
COMT met158val met/met TCI Self-transcendence 16.14 4.14 7 Healthy Korean students Ha 2004
COMT met158val met/val TCI Self-transcendence 14.26 6.35 38 Healthy Korean students Ha 2004
COMT met158val val/val TCI Self-transcendence 13.50 6.35 68 Healthy Korean students Ha 2004
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