An interaction between the norepinephrine transporter and monoamine oxidase A polymorphisms, and novelty-seeking personality traits in Korean females

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An interaction between the norepinephrine transporter and monoamine oxidase A polymorphisms, and novelty-seeking personality traits in Korean females
Authors: Boung-Chul Lee, Jae-Won Yang, So-Hee Lee, Seung-Hyun Kim, Sook-Haeng Joe, In-Kwa Jung, Ihn-Geun Choi, Byung-Joo Ham
Citation: Progress in neuro-psychopharmacology & biological psychiatry 32 (1): 238-232. 2008 January
Database(s): PubMed (PMID/17920180)
DOI: 10.1016/j.pnpbp.2007.08.014.
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Extract:

An interaction between the norepinephrine transporter and monoamine oxidase A polymorphisms, and novelty-seeking personality traits in Korean females reports a personality genetics study on the SLC6A2 C-182T and MAOA-uVNTR genetic polymorphisms and personality traits assessed with the Temperament and Character Inventory, Beck Depression Inventory and State Trait Anxiety Inventory (STAI).

[edit] Subjects

Subject group #1 (help)
Healthy female Korean nursing students
Subjects/♂/♀: 245 / 0 / 245
Age: 23.05 ±3.07 (–)
Nationality: Korean
Approval: Ethics Committee of the National Medical Center of Nursing
Databases:

Group 1 of 245 healthy female Korean nursing students with 0 males and 245 females were included in the study. The Korean group had a mean age of 23.05. The study on the human subjects was approved by the Ethics Committee of the National Medical Center of Nursing.

The text states that 245 women were recruited, but the results show data from only 242.

[edit] Results

Gene Polymorphism Genotype Inventory Trait Mean Std Subjects Recruitment PMID
MAOA uVNTR 3 TCI Novelty seeking 17.94 6.66 191 Healthy female Korean nursing students 17920180
MAOA uVNTR 4/4 TCI Novelty seeking 17.02 5.09 51 Healthy female Korean nursing students 17920180
SLC6A2 C-182T C TCI Novelty seeking 17.53 6.19 123 Healthy female Korean nursing students 17920180
SLC6A2 C-182T T/T TCI Novelty seeking 17.96 6.55 119 Healthy female Korean nursing students 17920180
MAOA uVNTR 3 TCI Harm avoidance 17.39 6.96 191 Healthy female Korean nursing students 17920180
MAOA uVNTR 4/4 TCI Harm avoidance 18.35 6.87 51 Healthy female Korean nursing students 17920180
SLC6A2 C-182T C TCI Harm avoidance 18.21 6.91 123 Healthy female Korean nursing students 17920180
SLC6A2 C-182T T/T TCI Harm avoidance 16.97 6.97 119 Healthy female Korean nursing students 17920180
MAOA uVNTR 3 TCI Reward dependence 16.21 3.52 191 Healthy female Korean nursing students 17920180
MAOA uVNTR 4/4 TCI Reward dependence 16.84 3.64 51 Healthy female Korean nursing students 17920180
SLC6A2 C-182T C TCI Reward dependence 16.14 3.72 123 Healthy female Korean nursing students 17920180
SLC6A2 C-182T T/T TCI Reward dependence 16.55 3.36 119 Healthy female Korean nursing students 17920180

[edit] Critique

  1. It seems not to be clear if the study has 245 or 242 subjects.
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