Association between serotonin transporter gene polymorphism and anxiety-related traits

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Association between serotonin transporter gene polymorphism and anxiety-related traits
Authors: Satomi Katsuragi, Hiroshi Kunugi, Akira Sano, Takashi Tsutsumi, Koichi Isogawa, Shinichiro Nanko, Jotaro Akiyoshi
Citation: Biological Psychiatry 45 (3): 368-370. 1999 February
Database(s): PubMed (PMID/10023516)
DOI: 10.1016/S0006-3223(98)00090-0.
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Extract:

Association between serotonin transporter gene polymorphism and anxiety-related traits is a personality genetics study between the 5-HTTLPR polymorphism of the serotonin transporter gene (SLC6A4) and the Tridimensional Personality Questionnaire.

The study involved 101 normal Japanese volunteers.

[edit] Results

Gene Polymorphism Genotype Inventory Trait Mean Std Subjects Recruitment PMID
SLC6A4 5-HTTLPR long/long TPQ Novelty seeking 15.00 1.82 4 Japanese medical students and doctors 10023516
SLC6A4 5-HTTLPR long/long TPQ Harm avoidance 17.00 2.94 4 Japanese medical students and doctors 10023516
SLC6A4 5-HTTLPR long/long TPQ Reward dependence 21.75 5.26 4 Japanese medical students and doctors 10023516
SLC6A4 5-HTTLPR long/short TPQ Novelty seeking 18.61 3.9 31 Japanese medical students and doctors 10023516
SLC6A4 5-HTTLPR long/short TPQ Harm avoidance 13.42 6.29 31 Japanese medical students and doctors 10023516
SLC6A4 5-HTTLPR long/short TPQ Reward dependence 19.16 4.18 31 Japanese medical students and doctors 10023516
SLC6A4 5-HTTLPR short/short TPQ Novelty seeking 18.08 4.14 66 Japanese medical students and doctors 10023516
SLC6A4 5-HTTLPR short/short TPQ Harm avoidance 17.53 5.77 66 Japanese medical students and doctors 10023516
SLC6A4 5-HTTLPR short/short TPQ Reward dependence 20.01 4.55 66 Japanese medical students and doctors 10023516
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