Association of GSK3β polymorphisms with brain structural changes in major depressive disorder

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Paper (help)
Association of GSK3β polymorphisms with brain structural changes in major depressive disorder
Authors: Becky Inkster, Thomas E. Nichols, Philipp G. Saemann, Dorothee P. Auer, Florian Holsboer, Pierandrea Muglia, Paul M. Matthews
Citation: Archives of General Psychiatry 66 (7): 721-728. 2009 July
Database(s): PubMed (PMID/19581563)
DOI: 10.1001/archgenpsychiatry.2009.70.
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Extract:

Association of GSK3β polymorphisms with brain structural changes in major depressive disorder reports a neuroimaging genetics study on 15 GSK3β single-nucleotide polymorphisms and regional grey matter volume differences in patients with recurrent major depressive disorder.

rs6438552 was found as the SNP with the most significant associations in brain regions: right and left superior temporal gyri and the right hippocampus.

[edit] Results

Table 2 display has Talairach coordinates from 15 SNPs.
Experiment #1 : rs6438552 (help)
Description: missing description
Scanning:
Topic: rs6438552 Major depressive disorder
Analysis:
Databases:

Anatomy
BA
x
y
z
No. vox
t
z
Coordinate search
Plot
1 38 -12 6 727 Brede Database Brede Wiki NeuroSynth SumsDB Not available
2 32 -24 -14 162 Brede Database Brede Wiki NeuroSynth SumsDB Not available
3 -48 -16 -2 Brede Database Brede Wiki NeuroSynth SumsDB Not available
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