Association study of a brain-derived neurotrophic factor (BDNF) val66met polymorphism and personality trait and intelligence in healthy young females

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Association study of a brain-derived neurotrophic factor (BDNF) val66met polymorphism and personality trait and intelligence in healthy young females
Authors: Shih-Jen Tsai, Chen-Jee Hong, Younger W.-Y. Yu, Tai-Jui Chen
Citation: Neuropsychobiology 49 (1): 13-16. 2004
Database(s): PubMed (PMID/14730195)
DOI: 10.1159/000075333.
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Association study of a brain-derived neurotrophic factor (BDNF) val66met polymorphism and personality trait and intelligence in healthy young females reports a personality genetics study on the rs6265 (val66met) genetic polymorphism in the BDNF gene with personality traits measured with the Tridimensional Personality Questionnaire and intelligence assessed with the WAIS-R.

[edit] Subjects

Subject group #1 (help)
Healthy Chinese female nursing students
Subjects/♂/♀: 114 / 0 / 114
Age: (19–21)
Nationality: Taiwanese
Approval: define approval
Databases:

Group 1 of 114 healthy Chinese female nursing students with 0 males and 114 females were included in the study. The Taiwanese group was from 19 up to 21 years old.


[edit] Results

Gene Polymorphism Genotype Inventory Trait Mean Std Subjects Recruitment PMID
BDNF met66val val/val TPQ Novelty seeking 19.0 5.0 26 Healthy Chinese female nursing students 14730195
BDNF met66val met/val TPQ Novelty seeking 17.8 4.4 54 Healthy Chinese female nursing students 14730195
BDNF met66val met/met TPQ Novelty seeking 18.3 5.1 34 Healthy Chinese female nursing students 14730195
BDNF met66val val/val TPQ Harm avoidance 13.7 7.4 26 Healthy Chinese female nursing students 14730195
BDNF met66val met/val TPQ Harm avoidance 16.2 6.0 54 Healthy Chinese female nursing students 14730195
BDNF met66val met/met TPQ Harm avoidance 15.2 6.3 34 Healthy Chinese female nursing students 14730195
BDNF met66val val/val TPQ Reward dependence 15.2 3.6 26 Healthy Chinese female nursing students 14730195
BDNF met66val met/val TPQ Reward dependence 15.2 3.1 54 Healthy Chinese female nursing students 14730195
BDNF met66val met/met TPQ Reward dependence 15.1 2.3 34 Healthy Chinese female nursing students 14730195
BDNF met66val val/val TPQ Persistence 4.0 2.0 26 Healthy Chinese female nursing students 14730195
BDNF met66val met/val TPQ Persistence 4.2 1.8 54 Healthy Chinese female nursing students 14730195
BDNF met66val met/met TPQ Persistence 3.4 1.6 34 Healthy Chinese female nursing students 14730195
BDNF met66val val/val WAIS-R Verbal intelligence 113.1 10.1 26 Healthy Chinese female nursing students 14730195
BDNF met66val met/val WAIS-R Verbal intelligence 113.1 10.7 54 Healthy Chinese female nursing students 14730195
BDNF met66val met/met WAIS-R Verbal intelligence 110.1 9.9 34 Healthy Chinese female nursing students 14730195
BDNF met66val val/val WAIS-R Performance intelligence 111.6 13.4 26 Healthy Chinese female nursing students 14730195
BDNF met66val met/val WAIS-R Performance intelligence 103.3 14.2 54 Healthy Chinese female nursing students 14730195
BDNF met66val met/met WAIS-R Performance intelligence 107.7 14.7 34 Healthy Chinese female nursing students 14730195
BDNF met66val val/val WAIS-R Intelligence 113.9 9.8 26 Healthy Chinese female nursing students 14730195
BDNF met66val met/val WAIS-R Intelligence 110.1 11.6 54 Healthy Chinese female nursing students 14730195
BDNF met66val met/met WAIS-R Intelligence 110.3 12.0 34 Healthy Chinese female nursing students 14730195
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