Association study of candidate variants from brain-derived neurotrophic factor and dystrobrevin-binding protein 1 with neuroticism, anxiety, and depression

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Association study of candidate variants from brain-derived neurotrophic factor and dystrobrevin-binding protein 1 with neuroticism, anxiety, and depression
Authors: Naomi R. Wray, Michael R. James, Herlina Y. Handoko, Troy Dumenil, Penelope A. Lind, Grant W. Montgomery, Nicholas G. Martin
Citation: Psychiatric genetics 18 (5): 219-225. 2008 October
Database(s): PubMed (PMID/18797396)
DOI: 10.1097/YPG.0b013e3283050aee.
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Association study of candidate variants from brain-derived neurotrophic factor and dystrobrevin-binding protein 1 with neuroticism, anxiety, and depression reports a personality genetics study and depression genetics association study on the genetic polymorphisms in the BDNF and DTNBP1 genes: val66met and rs3213207, rs1011313, rs2619528, rs1018381 and rs2619538.

[edit] Results

Personality scores are not reported. The only result reported is "no association was found" for both BDNF and DTNBP1.

The study is used in the meta-analysis with numbers N=950, SMD=0.02, p=0.82. It is not clear where the numbers came from.

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