Bipolar Disorder Neuroimaging Database

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Bipolar Disorder Neuroimaging Database
Abbreviations: BiND
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Category: Bipolar Disorder Neuroimaging Database
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Neuroinformatics database

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Bipolar Disorder Neuroimaging Database (BiND) is a database of studies collected for meta-analysis of magnetic resonance imaging studies in bipolar disorder. The corresponding publication is:

Matthew J. Kempton, John R. Geddes, Ulrich Ettinger, Steven C. R. Williams, Paul M. Grasby (2008). "Meta-analysis, database, and meta-regression of 98 structural imaging studies in bipolar disorder". Archives of General Psychiatry 65(9): missing pages. [1].

The data is available as a collection of sheets in the Excel file format:

http://www.bipolardatabase.org (http://sites.google.com/site/bipolardatabase/)

Contents

[edit] Variables of importance

The spreadsheets records detailed information about the studies, e.g., PubMed links, first author, year of publication, number of patients and controls, imaging method, diagnosis, name of brain region, volume of brain region (mean and standard deviation; for patients and controls; for left, right, total).

[edit] Brain regions

Of brain regions and brain characteristics with more than five publications a file in the database lists [2]:

  1. Hyperintensities
  2. Lateral Ventricle
  3. Brain volume
  4. Intracranial volume
  5. Hippocampus (left)
  6. Hippocampus (right)
  7. Cerebrum
  8. Gray matter
  9. Third ventricle
  10. White matter
  11. Lateral ventricle (left)
  12. Lateral ventricle (right)
  13. Temporal lobe (left)
  14. Temporal lobe (right)
  15. Hippocampus
  16. Thalamus
  17. Caudate
  18. Amygdala (left)
  19. Caudate (left)
  20. Amygdala (right)
  21. Caudate (right)
  22. Amygdala
  23. Thalamus (left)
  24. Thalamus (right)
  25. Putamen (left)
  26. Putamen (right)
  27. Corpus callosum area
  28. Globus pallidus
  29. Putamen

[edit] Other brain regions

(partial list)

  1. Cerebellar atrophy
  2. Corpus callosum length
  3. Cingulate (left)
  4. Subgenual prefrontal cortex (left)
  5. Cingulate (right)
  6. Subgenual prefrontal cortex (right)
  7. Temporal lobe

[edit] Meta-analysis

Topic Data Raw data Meta-analysis
AmygdalaBipolar disorderBiND Data CSV Meta-analysis
CaudateBipolar disorderBiND Data CSV Meta-analysis
Lateral ventriclesBipolar disorderBiND Data CSV Meta-analysis
Left subgenual cortexBipolar disorderBiND Data CSV Meta-analysis
ThalamusBipolar disorderBiND Data CSV Meta-analysis
Mass meta-analysis

[edit] Included studies

  1. An MRI study of subgenual prefrontal cortex in patients with familial and non-familial bipolar I disorder
  2. Anatomical MRI study of subgenual prefrontal cortex in bipolar and unipolar subjects
  3. Brain magnetic resonance imaging of structural abnormalities in bipolar disorder
  4. Cerebellar atrophy in schizophrenia and mania
  5. Cerebellar vermis dimensions on computerized tomographic scans of schizophrenic and bipolar patients
  6. Cerebral venticular enlargement in young manic males : A controlled CT study
  7. Cortical atrophy in schizophrenia and mania: a comparative CT study
  8. Larger amygdala volumes in first depressive episode as compared to recurrent major depression and healthy control subjects
  9. Structural brain abnormalities in first-episode mania
  10. Subgenual prefrontal cortex abnormalities in mood disorders
  11. Subgenual prefrontal cortex of child and adolescent bipolar patients: a morphometric magnetic resonance imaging study
  1. Bilateral hippocampal volume increase in patients with bipolar disorder and short-term lithium treatment (in the database it is listed as 2007, but the study is published in 2008) This might instead be Bilateral hippocampal volume increases after long-term lithium treatment in patients with bipolar disorder: a longitudinal MRI study.

[edit] See also

  1. Internet Brain Volume Database
  2. Major Depressive Disorder Neuroimaging Database (MaND)
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