DRD4 promoter SNPs and gender effects on extraversion in African Americans

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Paper (help)
DRD4 promoter SNPs and gender effects on extraversion in African Americans
Authors: E. B. Bookman, R. E. Taylor, L. Adams-Campbell, R. A. Kittles
Citation: Molecular Psychiatry 7 (7): 786-789. 2002
Database(s): PubMed (PMID/12192624)
DOI: 10.1038/sj.mp.4001075.
Link(s): http://www.nature.com/mp/journal/v7/n7/pdf/4001075a.pdf
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DRD4 promoter SNPs and gender effects on Extraversion in African Americans reports a personality genetics study on two DRD4 promoter polymorphisms: C-521T and C-616G with the personality trait extraversion assessed with NEO-FFI.

[edit] Subjects

Subject group #1 (help)
Healthy African Americans
Subjects/♂/♀: 71 / 33 / 38
Age: 32 (–)
Nationality: American
Approval: Howard University Institutional Review Board
Databases:

Group 1 of 71 healthy African Americans with 33 males and 38 females were included in the study. The American group had a mean age of 32. The study on the human subjects was approved by the Howard University Institutional Review Board.

[edit] Results

Gene Polymorphism Genotype Inventory Trait Mean Std Subjects Recruitment PMID
DRD4 C-616G C/C NEO-FFI Extraversion 28.4 4.41 5 Healthy African American males 12192624
DRD4 C-616G G NEO-FFI Extraversion 30.4 5.4 28 Healthy African American males 12192624
DRD4 C-521T C/C NEO-FFI Extraversion 30.7 5.44 10 Healthy African American males 12192624
DRD4 C-521T T NEO-FFI Extraversion 29.7 5.42 23 Healthy African American males 12192624
DRD4 C-616G C/C NEO-FFI Extraversion 31.3 3.48 4 Healthy African American females 12192624
DRD4 C-616T G NEO-FFI Extraversion 30.5 4.84 31 Healthy African American females 12192624
DRD4 C-521T C/C NEO-FFI Extraversion 32.1 3.71 13 Healthy African American females 12192624
DRD4 C-521T T NEO-FFI Extraversion 28.3 5.15 25 Healthy African American females 12192624
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