Decrease in thalamic volumes of pediatric patients with obsessive-compulsive disorder who are taking paroxetine

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Decrease in thalamic volumes of pediatric patients with obsessive-compulsive disorder who are taking paroxetine
Authors: Andrew R. Gilbert, Gregory J. Moore, Matcheri S. Keshavan, Lori Anne Paulson, Vikram Narula, Frank P. MacMaster, Carol M. Stewart, David R. Rosenberg
Citation: Archives of general psychiatry 57 (5): 449-446. 2000 May
Database(s): Bibliographics or graphical review in IBVD PubMed (PMID/10807485)
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Decrease in thalamic volumes of pediatric patients with obsessive-compulsive disorder who are taking paroxetine reports a structural neuroimaging study with magnetic resonance imaging on pediatric patients with obsessive-compulsive disorder.

[edit] Subjects

Subject group #1 (help)
Pediatric obsessive-compulsive disorder patients
Description: Pediatric right-hand dominant psychotropic-naïve obsessive-compulsive disorder outpatients
Subjects/♂/♀: 21 / 7 / 14
Age: 12.35 ±2.93 (8–17)
Nationality: American
Approval: define approval
Databases: IBVD

Group 1 of 21 pediatric obsessive-compulsive disorder patients with 7 males and 14 females were included in the study. The American group had a mean age of 12.35 with a range from 8 to 17.


[edit] Results

Brain volume results are reported in Table 2 for 4 brain regions: intracranial, thalamus, left thalamus and right thalamus.

[edit] Related papers

  1. Brain structural abnormalities in psychotropic drug-naive pediatric patients with obsessive-compulsive disorder
  2. Pituitary volume in pediatric obsessive-compulsive disorder
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