Depression duration but not age predicts hippocampal volume loss in medically healthy women with recurrent major depression

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Paper (help)
Depression duration but not age predicts hippocampal volume loss in medically healthy women with recurrent major depression
Authors: Yvette I. Sheline, Milan Sanghavi, Mark A. Mintun, Mokhtar H. Gado
Citation: The Journal of Neuroscience 19 (12): 5034-5043. 1999 June
Database(s): Bibliographics or graphical review in IBVD PubMed (PMID/10366636)
DOI: Define doi.
Link(s): http://www.jneurosci.org/cgi/content/full/19/12/5034
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Depression duration but not age predicts hippocampal volume loss in medically healthy women with recurrent major depression reports a study on the brain volume of hippocampus and amygdala with structural magnectic resonance imaging on patient with depression and matched controls.

[edit] Subjects

Subject group #1 (help)
Depressive women
Subjects/♂/♀: 24 / 0 / 24
Age: 54 (23–86)
Handedness: Right
Nationality: define nationality
Approval: define approval
Databases: IBVD

Group 1 of 24 right-handed depressive women with 0 males and 24 females were included in the study.

The group had a mean age of 54 with a range from 23 to 86.
Subject group #2 (help)
Case-matched women
Subjects/♂/♀: 24 / 0 / 24
Age: (–)
Nationality: define nationality
Approval: define approval
Databases: IBVD

Group 2 of 24 case-matched women with 0 males and 24 females were included in the study.


[edit] Results

Table 2 with 20 brain volume [1]
#
Mean
Std
SEM
Unit
Anatomy
Group
No. (M/F)
Age
1 2230 323 mm3 Left hippocampus Depressed (/) (–)
2 2482 305 mm3 Left hippocampus Matched controls (/) (–)
3 2264 320 mm3 Right hippocampus Depressed (/) (–)
4 2468 309 mm3 Right hippocampus Matched controls (/) (–)
5 4496 602 mm3 Hippocampus Depressed (/) (–)
6 4951 601 mm3 Hippocampus Matched controls (/) (–)
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