Gender-common and -specific neuroanatomical basis of human anxiety-related personality traits reports a personality neuroimaging study with magnetic resonance imaging, voxel-based morphometry and a Japanese version of the Temperament and Character Inventory (TCI).
The study has a relatively large number of subjects: 183.
Subjects were score on all 7 traits of TCI, but the reporting of the results is mostly for the harm avoidance personality trait.
Group 1 of 183 right-handed japanese with 117 males and 66 females were included in the study.
The Japanese group was from 21 up to 40 years old.
The study on the human subjects was approved by the Ethical committee of the University of Tokyo Hospital.
For sMRI 3D Fourier transform spoiled gradient recalled scans were acquired with a 1.5T GE Medical Systems Signa Horizon Lx version 8.2.
The brain scans are spatially normalized to the International Consortium for Brain Mapping template.
 Negative correlation between harm avoidance and grey matter
Table 2, part 1 with 1 coordinate. 1 coordinate in text on page 48. This coordinate is reported to be not significant
 Interaction with gender on correlation between harm avoidance and grey matter
Table 2, part 2 with 1 coordinate. A coordinate in the right hippocampus is mentioned in the text, but this coordinate in not significant with a z-score of 0.88.
 Negative correlation between harm avoidance and grey matter in females
 Positive correlation between reward dependence and grey matter
A single coordinate is reported at the bottom of the text of page 51.
- P-values are thresholded on uncorrected <0.001 and false discovery rate set to <0.05. Small volume correction was applied to hippocampus, amygdala and prefrontal cortex, — seeming family-wise error corrected across voxels.
- It is not clear if the coordinate in the hippocampus for reward dependence is the only coordinate in the brain for that threshold.