High familial risk for mood disorder is associated with low dorsolateral prefrontal cortex serotonin transporter binding

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High familial risk for mood disorder is associated with low dorsolateral prefrontal cortex serotonin transporter binding
Authors: Vibe Gedsø Frøkjær, Maj Vinberg, David Erritzøe, Claus Svarer, William F. C. Baaré, Esben Budtz-Jørgensen, Karine Madsen, Jacob Madsen, Lars V. Kessing, Gitte Moos Knudsen
Citation: NeuroImage 46 (2): 360-366. 2009 June
Database(s): Google Scholar cites PubMed (PMID/19233297)
DOI: 10.1016/j.neuroimage.2009.02.008.
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Extract:

High familial risk for mood disorder is associated with low dorsolateral prefrontal cortex serotonin transporter binding reports a positron emission tomography study with the carbon-11 DASB radioligand for the serotonin transporter among healthy twins that had a co-twin that were either affected by a mood disorder or not. The study found some difference in the dorsolateral prefrontal cortex.

[edit] Subjects

Subject group #1 (help)
Healthy twin with mood disorder affected co-twin
Subjects/♂/♀: 9 /  /
Age: 32.2 ±4.2 (–)
Nationality: Danish
Approval: define approval
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Group 1 of 9 healthy twin with mood disorder affected co-twin were included in the study.

The Danish group had a mean age of 32.2.
Subject group #2 (help)
Healthy twin with healthy co-twin
Subjects/♂/♀: 11 /  /
Age: 32.4 ±5.0 (–)
Nationality: Danish
Approval: define approval
Databases:

Group 2 of 11 healthy twin with healthy co-twin were included in the study. The Danish group had a mean age of 32.4.

Although the study is performed on twins it is not a twin study.

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