Increased activation in the right insula during risk-taking decision making is related to harm avoidance and neuroticism reports a functional magnetic resonance imaging study on healthy subjects and with personality assessment.
A group of 17 healthy with 11 males and 6 females were included in the study.
The American group had a mean age of 38.3 with a range from 27 to 53.
The study on the human subjects was approved by the UCSD Human Research Protection Program.
The subjects participated under approval of UCSD Human Research Protection Program.
All subjects completed Temperament and Character Inventory and NEO-FFI questionnaires.
(There is a rather little standard deviation on the age compared to the max age)
Results were obtained with AFNI and the cluster-size threshold based on Forman and others.
So seemingly the P-values are corrected on the cluster level with <0.05(!?).
 Risky versus safe response
Table I with 5 coordinates on page 1444.
 Risky versus punished trials
Table 2 with 3 coordinates on page 1444.
- ↑ S. D. Forman, J. D. Cohen, M. Fitzgerald, W. F. Eddy, M. A. Mintun, D. C. Noll (1995). "Improved assessment of significant activation in functional magnetic resonance imaging (fMRI): use of a cluster-size threshold". Magnetic Resonance in Medicine 33: 636-547.