Interaction between brain-derived neurotrophic factor val66met polymorphism and recent negative stressor in harm avoidance

From Brede Wiki
Jump to: navigation, search
Paper (help)
Interaction between brain-derived neurotrophic factor val66met polymorphism and recent negative stressor in harm avoidance
Authors: Seog Ju Kim, Seong-Jin Cho, Ha Min Jang, Jonghan Shin, Pil-Whan Park, Yu Jin Lee, In Hee Cho, Jung-Eun Choi, Heon-Jeong Lee
Citation: Neuropsychobiology 61 (1): 19-26. 2010
Database(s): PubMed (PMID/19923862)
DOI: 10.1159/000258639.
Link(s):
Search
Web: Bing Google Yahoo!Google PDF
Article: BASE Google Scholar PubMed
Restricted: DTU Digital Library
Other: NIF
Services
Format: BibTeX Template from PMID
Extract:

Interaction between brain-derived neurotrophic factor val66met polymorphism and recent negative stressor in harm avoidance reports a personality genetics study. on the rs6265 (val66met) genetic polymorphism in the BDNF gene, personality traits assessed with the Temperament and Character Inventory and negative life stressor collected by interview.

[edit] Subjects

Subject group #1 (help)
Korean community-dwelling adults
Subjects/♂/♀: 391 / 152 / 239
Age: 43.2 ±14.1 (19–)
Nationality: Korean
Approval: Institutional Review Board at the Gachon University of Medicine and Science
Databases:

Group 1 of 391 korean community-dwelling adults with 152 males and 239 females were included in the study. The Korean group had a mean age of 43.2 The study on the human subjects was approved by the Institutional Review Board at the Gachon University of Medicine and Science.

Subjects were divided into two groups:

  1. Korean community-dwelling adults with negative life stressors
  2. Korean community-dwelling adults without negative life stressors

A negative life stressor would be one of the following:

  1. Bereavement involving family or close friends
  2. Serious illness of self or family
  3. Serious economic crisis
  4. Unwanted retirement or having been fired
  5. Severe conflicts with family, friends, relatives or colleagues
  6. Divorce or unwanted end of relationship

[edit] Results

Gene Polymorphism Genotype Inventory Trait Mean Std Subjects Recruitment PMID
BDNF met66val met/met TCI Novelty seeking 16.86 5.06 67 Korean community-dwelling adults without negative life stressors 19923862
BDNF met66val met/val TCI Novelty seeking 16.15 5.49 139 Korean community-dwelling adults without negative life stressors 19923862
BDNF met66val val/val TCI Novelty seeking 15.82 4.95 84 Korean community-dwelling adults without negative life stressors 19923862
BDNF met66val met/met TCI Harm avoidance 16.02 6.62 67 Korean community-dwelling adults without negative life stressors 19923862
BDNF met66val met/val TCI Harm avoidance 15.55 7.16 139 Korean community-dwelling adults without negative life stressors 19923862
BDNF met66val val/val TCI Harm avoidance 16.24 5.79 84 Korean community-dwelling adults without negative life stressors 19923862
BDNF met66val met/met TCI Reward dependence 15.02 3.24 67 Korean community-dwelling adults without negative life stressors 19923862
BDNF met66val met/val TCI Reward dependence 15.06 3.23 139 Korean community-dwelling adults without negative life stressors 19923862
BDNF met66val val/val TCI Reward dependence 15.33 3.37 84 Korean community-dwelling adults without negative life stressors 19923862
BDNF met66val met/met TCI Persistence 4.69 1.81 67 Korean community-dwelling adults without negative life stressors 19923862
BDNF met66val met/val TCI Persistence 4.96 1.68 139 Korean community-dwelling adults without negative life stressors 19923862
BDNF met66val val/val TCI Persistence 4.52 1.88 84 Korean community-dwelling adults without negative life stressors 19923862
BDNF met66val met/met TCI Self-directedness 27.50 7.13 67 Korean community-dwelling adults without negative life stressors 19923862
BDNF met66val met/val TCI Self-directedness 26.93 7.74 139 Korean community-dwelling adults without negative life stressors 19923862
BDNF met66val val/val TCI Self-directedness 28.07 6.88 84 Korean community-dwelling adults without negative life stressors 19923862
BDNF met66val met/met TCI Cooperativeness 30.47 5.15 67 Korean community-dwelling adults without negative life stressors 19923862
BDNF met66val met/val TCI Cooperativeness 30.27 5.42 139 Korean community-dwelling adults without negative life stressors 19923862
BDNF met66val val/val TCI Cooperativeness 30.85 5.78 84 Korean community-dwelling adults without negative life stressors 19923862
BDNF met66val met/met TCI Self-transcendence 14.25 6.93 67 Korean community-dwelling adults without negative life stressors 19923862
BDNF met66val met/val TCI Self-transcendence 13.27 6.26 139 Korean community-dwelling adults without negative life stressors 19923862
BDNF met66val val/val TCI Self-transcendence 14.30 6.43 84 Korean community-dwelling adults without negative life stressors 19923862
BDNF met66val met/met TCI Novelty seeking 16.22 5.24 27 Korean community-dwelling adults with negative life stressor 19923862
BDNF met66val met/val TCI Novelty seeking 15.82 5.08 49 Korean community-dwelling adults with negative life stressor 19923862
BDNF met66val val/val TCI Novelty seeking 16.92 5.32 25 Korean community-dwelling adults with negative life stressor 19923862
BDNF met66val met/met TCI Harm avoidance 14.56 6.32 27 Korean community-dwelling adults with negative life stressor 19923862
BDNF met66val met/val TCI Harm avoidance 16.41 7.53 49 Korean community-dwelling adults with negative life stressor 19923862
BDNF met66val val/val TCI Harm avoidance 20.21 5.59 25 Korean community-dwelling adults with negative life stressor 19923862
BDNF met66val met/met TCI Reward dependence 15.63 2.54 27 Korean community-dwelling adults with negative life stressor 19923862
BDNF met66val met/val TCI Reward dependence 15.96 3.48 49 Korean community-dwelling adults with negative life stressor 19923862
BDNF met66val val/val TCI Reward dependence 16.13 3.15 25 Korean community-dwelling adults with negative life stressor 19923862
BDNF met66val met/met TCI Persistence 5.19 1.71 27 Korean community-dwelling adults with negative life stressor 19923862
BDNF met66val met/val TCI Persistence 4.82 1.94 49 Korean community-dwelling adults with negative life stressor 19923862
BDNF met66val val/val TCI Persistence 4.71 1.52 25 Korean community-dwelling adults with negative life stressor 19923862
BDNF met66val met/met TCI Self-directedness 27.22 6.33 27 Korean community-dwelling adults with negative life stressor 19923862
BDNF met66val met/val TCI Self-directedness 26.16 6.79 49 Korean community-dwelling adults with negative life stressor 19923862
BDNF met66val val/val TCI Self-directedness 24.29 9.17 25 Korean community-dwelling adults with negative life stressor 19923862
BDNF met66val met/met TCI Cooperativeness 30.67 4.06 27 Korean community-dwelling adults with negative life stressor 19923862
BDNF met66val met/val TCI Cooperativeness 31.22 4.33 49 Korean community-dwelling adults with negative life stressor 19923862
BDNF met66val val/val TCI Cooperativeness 29.75 7.51 25 Korean community-dwelling adults with negative life stressor 19923862
BDNF met66val met/met TCI Self-transcendence 14.41 7.01 27 Korean community-dwelling adults with negative life stressor 19923862
BDNF met66val met/val TCI Self-transcendence 12.59 6.45 49 Korean community-dwelling adults with negative life stressor 19923862
BDNF met66val val/val TCI Self-transcendence 13.46 5.54 25 Korean community-dwelling adults with negative life stressor 19923862
Personal tools