Lack of association between polymorphisms of the dopamine receptor D4 and dopamine transporter genes and personality traits in a Korean population

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Lack of association between polymorphisms of the dopamine receptor D4 and dopamine transporter genes and personality traits in a Korean population
Authors: Se Joo Kim, Young Shin Kim, Chan-Hyung Kim, Hong Shick Lee
Citation: Yonsei Medical Journal 47 (6): 787-782. 2006 December
Database(s): PubMed (PMID/17191306)
DOI: 10.3349/ymj.2006.47.6.787.
PMCID:2687817
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Extract:

Lack of association between polymorphisms of the dopamine receptor D4 and dopamine transporter genes and personality traits in a Korean reports a personality genetics study on DRD4 exon 3 VNTR and dopamine transporter gene (SLC6A3/DAT1) 40-bp VNTR genetic polymorphisms with personality traits assessed with the Temperament and Character Inventory.

[edit] Subjects

Subject group #1 (help)
Healthy Korean hospital nurses, students and volunteers
Subjects/♂/♀: 214 / 102 / 112
Age: (21–35)
Nationality: Korean
Approval: Yongdong Severance Hospital
Databases:

Group 1 of 214 healthy Korean hospital nurses, students and volunteers with 102 males and 112 females were included in the study. The Korean group was from 21 up to 35 years old. The study on the human subjects was approved by the Yongdong Severance Hospital.

[edit] Results

Gene Polymorphism Genotype Inventory Trait Mean Std Subjects Recruitment PMID
DRD4 Exon 3 VNTR short/short TCI Novelty seeking 17.98 7.18 205 Healthy Korean hospital nurses and students and volunteers 17191306
DRD4 Exon 3 VNTR short/short TCI Harm avoidance 16.82 7.18 205 Healthy Korean hospital nurses and students and volunteers 17191306
DRD4 Exon 3 VNTR short/short TCI Reward dependence 15.95 3.77 205 Healthy Korean hospital nurses and students and volunteers 17191306
DRD4 Exon 3 VNTR short/short TCI Persistence 4.07 1.83 205 Healthy Korean hospital nurses and students and volunteers 17191306
DRD4 Exon 3 VNTR long TCI Novelty seeking 20.00 8.85 9 Healthy Korean hospital nurses and students and volunteers 17191306
DRD4 Exon 3 VNTR long TCI Harm avoidance 12.33 8.14 9 Healthy Korean hospital nurses and students and volunteers 17191306
DRD4 Exon 3 VNTR long TCI Reward dependence 14.78 4.47 9 Healthy Korean hospital nurses and students and volunteers 17191306
DRD4 Exon 3 VNTR long TCI Persistence 4.11 1.36 9 Healthy Korean hospital nurses and students and volunteers 17191306
SLC6A3 40-bp VNTR -10/10 TCI Novelty seeking 16.90 4.42 22 Healthy Korean hospital nurses and students and volunteers 17191306
SLC6A3 40-bp VNTR -10/10 TCI Harm avoidance 17.90 6.67 22 Healthy Korean hospital nurses and students and volunteers 17191306
SLC6A3 40-bp VNTR -10/10 TCI Reward dependence 15.16 4.55 22 Healthy Korean hospital nurses and students and volunteers 17191306
SLC6A3 40-bp VNTR -10/10 TCI Persistence 4.04 1.99 22 Healthy Korean hospital nurses and students and volunteers 17191306
SLC6A3 40-bp VNTR 10/10 TCI Novelty seeking 18.18 5.81 192 Healthy Korean hospital nurses and students and volunteers 17191306
SLC6A3 40-bp VNTR 10/10 TCI Harm avoidance 16.70 7.37 192 Healthy Korean hospital nurses and students and volunteers 17191306
SLC6A3 40-bp VNTR 10/10 TCI Reward dependence 15.97 3.64 192 Healthy Korean hospital nurses and students and volunteers 17191306
SLC6A3 40-bp VNTR 10/10 TCI Persistence 4.01 1.81 192 Healthy Korean hospital nurses and students and volunteers 17191306
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