Mapping structural brain alterations in obsessive-compulsive disorder

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Mapping structural brain alterations in obsessive-compulsive disorder
Authors: Jesús Pujol, Carles Soriano-Mas, Pino Alonso, Narcís Cardoner, José M. Menchón, Joan Deus, Julio Vallejo
Citation: Archives of general psychiatry 61 (7): 720-730. 2004 July
Database(s): PubMed (PMID/15237084)
DOI: 10.1001/archpsyc.61.7.720.
Link(s): http://archpsyc.ama-assn.org/cgi/reprint/61/7/720.pdf
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Mapping structural brain alterations in obsessive-compulsive disorder describes a study on brain volumes of obsessive-compulsive disorder patients with magnetic resonance imaging.

Contents

[edit] Subjects

Subject group #1 (help)
Obsessive-compulsive disorder patients
Subjects/♂/♀: 72 / 40 / 32
Age: 29.8 ±10.5 (18–60)
Nationality: Spanish
Approval: Institutional review board (Hospital of Bellvitge)
Databases:

Group 1 of 72 obsessive-compulsive disorder patients with 40 males and 32 females were included in the study. The Spanish group had a mean age of 29.8 with a range from 18 to 60.

The study on the human subjects was approved by the Institutional review board (Hospital of Bellvitge).
Subject group #2 (help)
Controls
Subjects/♂/♀: 72 / 40 / 32
Age: 30.1 ±10.2 (18–57)
Nationality: Spanish
Approval: Institutional review board (Hospital of Bellvitge)
Databases:

Group 2 of 72 controls with 40 males and 32 females were included in the study. The Spanish group had a mean age of 30.1 with a range from 18 to 57. The study on the human subjects was approved by the Institutional review board (Hospital of Bellvitge). 72 patients and 72 controls.

[edit] Results

[edit] Brain volume

Results for mean volume is given for intracranial volume and gray matter volume on page 723.

[edit] Voxel-based morphometry


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[edit] Related papers

  1. Brain structural correlates of depressive comorbidity in obsessive-compulsive disorder
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