Monoamine oxidase A gene promoter polymorphism affects novelty seeking and reward dependence in healthy study participants

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Monoamine oxidase A gene promoter polymorphism affects novelty seeking and reward dependence in healthy study participants
Authors: Hiroaki Shiraishi, Akihito Suzuki, Takashi Fukasawa, Toshiaki Aoshima, Yukihiro Ujiie, Genki Ishii, Koichi Otani
Citation: Psychiatric genetics 16 (2): 55-58. 2006 April
Database(s): PubMed (PMID/16538181)
DOI: 10.1097/01.ypg.0000199447.62044.ef.
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Monoamine oxidase A gene promoter polymorphism affects novelty seeking and reward dependence in healthy study participants reports a personality genetics study on the MAOA-uVNTR genetic polymorphism.

[edit] Subjects

Subject group #1 (help)
Japanese hospital staff and students
Subjects/♂/♀: 324 / 144 / 178
Age: 29.9 ±9.1 (–)
Nationality: Japanese
Approval: Ethics Committee of the Yamagata University School of Medicine
Databases:

Group 1 of 324 japanese hospital staff and students with 144 males and 178 females were included in the study. The Japanese group had a mean age of 29.9. The study on the human subjects was approved by the Ethics Committee of the Yamagata University School of Medicine.

[edit] Results

Gene Polymorphism Genotype Inventory Trait Mean Std Subjects Recruitment PMID
MAOA uVNTR 3 TCI Novelty seeking 20.6 5.1 145 Japanese hospital staff and students 16538181
MAOA uVNTR 3/4 TCI Novelty seeking 21.5 5.3 97 Japanese hospital staff and students 16538181
MAOA uVNTR 4 TCI Novelty seeking 22.8 4.9 80 Japanese hospital staff and students 16538181
MAOA uVNTR 3 TCI Reward dependence 15.9 3.6 145 Japanese hospital staff and students 16538181
MAOA uVNTR 3/4 TCI Reward dependence 16.8 3.2 97 Japanese hospital staff and students 16538181
MAOA uVNTR 4 TCI Reward dependence 17.3 3.2 80 Japanese hospital staff and students 16538181
MAOA uVNTR 3 TCI Self-transcendence 8.9 4.3 145 Japanese hospital staff and students 16538181
MAOA uVNTR 3/4 TCI Self-transcendence 10.9 5.2 97 Japanese hospital staff and students 16538181
MAOA uVNTR 4 TCI Self-transcendence 8.8 5.0 80 Japanese hospital staff and students 16538181
MAOA uVNTR 3 TCI Harm avoidance 20.0 5.8 145 Japanese hospital staff and students 16538181
MAOA uVNTR 3/4 TCI Harm avoidance 19.4 5.9 97 Japanese hospital staff and students 16538181
MAOA uVNTR 4 TCI Harm avoidance 18.9 6.4 80 Japanese hospital staff and students 16538181
MAOA uVNTR 3 TCI Persistence 4.1 1.6 145 Japanese hospital staff and students 16538181
MAOA uVNTR 3/4 TCI Persistence 4.3 1.8 97 Japanese hospital staff and students 16538181
MAOA uVNTR 4 TCI Persistence 4.0 2.0 80 Japanese hospital staff and students 16538181
MAOA uVNTR 3 TCI Self-directedness 27.6 6.5 145 Japanese hospital staff and students 16538181
MAOA uVNTR 3/4 TCI Self-directedness 27.0 7.0 97 Japanese hospital staff and students 16538181
MAOA uVNTR 4 TCI Self-directedness 28.5 6.4 80 Japanese hospital staff and students 16538181
MAOA uVNTR 3 TCI Cooperativeness 28.7 4.7 145 Japanese hospital staff and students 16538181
MAOA uVNTR 3/4 TCI Cooperativeness 28.6 4.9 97 Japanese hospital staff and students 16538181
MAOA uVNTR 4 TCI Cooperativeness 28.6 4.8 80 Japanese hospital staff and students 16538181
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