Neuroticism

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Topic (help)
Neuroticism
Variations:	Neurotic
Parents:	Personality trait Revised NEO Personality Inventory
Children:	Anxiety trait Hostility trait Depression trait Self-consciousness Impulsiveness Vulnerability trait
Databases:	Wikipedia
Search:	DOAJ MeSH NeuroLex Open J-Gate

Neuroticism is a personality trait. It is measured with the NEO family of personality tests.

It is related to the harm avoidance trait from the Cloninger personality questionnaires.

In NEO PI-R neuroticism has the following subtraits:

1. Anxiety
2. Hostility
3. Depression
4. Self-consciousness
5. Impulsiveness
6. Vulnerability to stress

A genome-wide association study among 6148 individuals pointed to rs18497010 in TMEM16D and rs362584 in SNAP25 (among others) as associated with neuroticism though neither of these showed any particular association in replication.^[1]

Contents 1 Papers 1.1 Neuroimaging papers 1.2 Personality genetics papers 2 Reference

[edit] Papers

[edit] Neuroimaging papers

1. Amygdala gray matter concentration is associated with extraversion and neuroticism
2. Anterior insula reactivity during certain decisions is associated with neuroticism
3. Emotional conflict and neuroticism: Personality dependent activation in the amygdala and subgenual anterior cingulate
4. Frontolimbic serotonin 2A receptor binding in healthy subjects is associated with personality risk factors for affective disorder
5. Inverse relationship between serotonin 5-HT1A receptor binding and anxiety: a 11C WAY-100635 PET investigation in healthy volunteers
6. Negative association of neuroticism with brain volume ratio in healthy humans
7. Neuroanatomical correlates of extraversion and neuroticism
8. Neuroanatomical correlates of personality in the elderly
9. Neuroticism modulates amygdala-prefrontal connectivity in response to negative emotional facial expressions
10. Regional cerebral brain metabolism correlates of neuroticism and extraversion
11. Relationship between neuroticism personality trait and serotonin transporter binding
12. Resting brain metabolic correlates of neuroticism and extraversion in young men
13. The complex minds of teenagers: Neuroanatomy of personality differs between sexes

[edit] Personality genetics papers

1. Genome-wide association scan for five major dimensions of personality
2. Neuroticism is not associated with the serotonin transporter (5-HTTLPR) polymorphism
3. Neuroticism mediates the association of the serotonin transporter gene with lifetime major depression
4. Relationship between XBP1 genotype and personality traits assessed by TCI and NEO-FFI

[edit] Reference

1. ↑ A. Terracciano, S. Sanna, M. Uda, B. Deiana, G. Usala, F. Busonero, A. Maschio, M. Scally, N. Patriciu, W.-M. Chen, M. A. Distel (missing year). "Genome-wide association scan for five major dimensions of personality". Molecular Psychiatry missing volume: missing pages. doi: 10.1038/mp.2008.113. PMID:18957941.