No association between the TPH A218C polymorphism and personality traits in Japanese healthy subjects

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No association between the TPH A218C polymorphism and personality traits in Japanese healthy subjects
Authors: Akihito Suzuki, Takashi Fukasawa, Hiroaki Shiraishi, Genki Ishii, Shingo Oshino, Toshiaki Aoshima, Koichi Otani
Citation: Progress in neuro-psychopharmacology & biological psychiatry 31 (2): 395-398. 2007 March
Database(s): PubMed (PMID/17116352)
DOI: 10.1016/j.pnpbp.2006.10.003.
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No association between the TPH A218C polymorphism and personality traits in Japanese healthy subjects reports a personality genetics study on TPH1 A218C genetics polymorphism and personality traits assessed with the Temperament and Character Inventory.

[edit] Results

Gene Polymorphism Genotype Inventory Trait Mean Std Subjects Recruitment PMID
TPH1 A218C A/A TCI Novelty seeking 21.2 5.4 93 Japanese medical staff and students 17116352
TPH1 A218C A/A TCI Harm avoidance 18.4 6.4 93 Japanese medical staff and students 17116352
TPH1 A218C A/A TCI Reward dependence 16.5 4.0 93 Japanese medical staff and students 17116352
TPH1 A218C A/A TCI Persistence 4.2 1.8 93 Japanese medical staff and students 17116352
TPH1 A218C A/A TCI Self-directedness 28.7 6.5 93 Japanese medical staff and students 17116352
TPH1 A218C A/A TCI Cooperativeness 28.9 6.0 93 Japanese medical staff and students 17116352
TPH1 A218C A/A TCI Self-transcendence 10.2 5.1 93 Japanese medical staff and students 17116352
TPH1 A218C A/C TCI Novelty seeking 21.9 4.8 177 Japanese medical staff and students 17116352
TPH1 A218C A/C TCI Harm avoidance 19.9 5.7 177 Japanese medical staff and students 17116352
TPH1 A218C A/C TCI Reward dependence 16.5 3.4 177 Japanese medical staff and students 17116352
TPH1 A218C A/C TCI Persistence 4.1 1.8 177 Japanese medical staff and students 17116352
TPH1 A218C A/C TCI Self-directedness 27.6 6.6 177 Japanese medical staff and students 17116352
TPH1 A218C A/C TCI Cooperativeness 28.5 4.6 177 Japanese medical staff and students 17116352
TPH1 A218C A/C TCI Self-transcendence 9.3 4.6 177 Japanese medical staff and students 17116352
TPH1 A218C C/C TCI Novelty seeking 20.9 5.3 75 Japanese medical staff and students 17116352
TPH1 A218C C/C TCI Harm avoidance 19.5 5.9 75 Japanese medical staff and students 17116352
TPH1 A218C C/C TCI Reward dependence 16.0 3.3 75 Japanese medical staff and students 17116352
TPH1 A218C C/C TCI Persistence 4.1 1.7 75 Japanese medical staff and students 17116352
TPH1 A218C C/C TCI Self-directedness 27.5 6.7 75 Japanese medical staff and students 17116352
TPH1 A218C C/C TCI Cooperativeness 28.1 4.2 75 Japanese medical staff and students 17116352
TPH1 A218C C/C TCI Self-transcendence 8.9 4.8 75 Japanese medical staff and students 17116352
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