Orbital frontal and amygdala volume reductions in obsessive-compulsive disorder

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Paper (help)
Orbital frontal and amygdala volume reductions in obsessive-compulsive disorder
Authors: Philip R. Szeszko, Delbert Robinson, Jose Ma J. Alvir, Robert M. Bilder, Todd Lencz, Manzar Ashtari, Houwei Wu, Bernhard Bogerts
Citation: Archives of general psychiatry 56 (10): 913-919. 1999 October
Database(s): PubMed (PMID/10530633)
DOI: 10.1001/archpsyc.56.10.913.
Link(s): http://archpsyc.jamanetwork.com/data/Journals/PSYCH/5101/yoa8349.pdf
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Orbital frontal and amygdala volume reductions in obsessive-compulsive disorder report a study on the brain volume of patients with obsessive-compulsive disorder (OCD) and structural magnetic resonance imaging.

[edit] Subjects

Subject group #1 (help)
Obsessive-compulsive disorder patients
Subjects/♂/♀: 26 / 14 / 12
Age: 32.2 ±8.0 (19–44)
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Group 1 of 26 obsessive-compulsive disorder patients with 14 males and 12 females were included in the study.

The group had a mean age of 32.2 with a range from 19 to 44.
Subject group #2 (help)
Healthy
Subjects/♂/♀: 26 / 16 / 10
Age: 29.8 ±6.3 (20–45)
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Group 2 of 26 healthy with 16 males and 10 females were included in the study. The group had a mean age of 29.8 with a range from 20 to 45.


The subjects are the same as in the paper Reduced caudate nucleus volume in obsessive-compulsive disorder.

[edit] Results

Mean brain volume and standard deviations are reported for total, right and left: superior frontal gyrus, anterior cingulate gyrus, orbital frontal region, hippocampus, amygdala in Table 1.

Brain asymmetry results are also reported for the 5 regions.

[edit] Related papers

  1. Reduced caudate nucleus volume in obsessive-compulsive disorder
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