Anxiety traits associated with a polymorphism in the serotonin transporter gene regulatory region in the Japanese

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Anxiety traits associated with a polymorphism in the serotonin transporter gene regulatory region in the Japanese
Authors: Fumiyo Murakami, T. Shimomura, Kazuhiko Kotani, Shiro Ikawa, Eiji Nanba, Kaori Adachi
Citation: Journal of Human Genetics 44 (1): 15-17. 1999
Database(s): PubMed (PMID/9929970)
DOI: 10.1007/s100380050098.
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Anxiety traits associated with a polymorphism in the serotonin transporter gene regulatory region in the Japanese reports a personality genetics study on the serotonin transporter gene 5-HTTLPR genetic polymorphism with personality traits asssessed with the Self-rating questionnaire for anxiety and depression[1] (SRQ-AD).

[edit] Subjects

Subject group #1 (help)
Japanese volunteers
Subjects/♂/♀: 189 / 117 / 72
Age: 49.3 ±14.2 (19–81)
Nationality: Japanese
Approval: Tottori University's Ethic Committee for Experimentaion on Humans
Databases:

Group 1 of 189 japanese volunteers with 117 males and 72 females were included in the study. The Japanese group had a mean age of 49.3 with a range from 19 to 81. The study on the human subjects was approved by the Tottori University's Ethic Committee for Experimentaion on Humans.

[edit] Results

Gene Polymorphism Genotype Inventory Trait Mean Std Subjects Recruitment PMID
SLC6A4 5-HTTLPR long SRQ-AD SRQ-AD 4.8 3.6 65 Healthy Japanese volunteers 9929970
SLC6A4 5-HTTLPR short/short SRQ-AD SRQ-AD 5.3 3.8 124 Healthy Japanese volunteers 9929970
SLC6A4 5-HTTLPR long SRQ-AD Anxiety 2.6 2.0 65 Healthy Japanese volunteers 9929970
SLC6A4 5-HTTLPR short/short SRQ-AD Anxiety 3.3 2.1 124 Healthy Japanese volunteers 9929970
SLC6A4 5-HTTLPR long SRQ-AD Depression 2.8 3.0 65 Healthy Japanese volunteers 9929970
SLC6A4 5-HTTLPR short/short SRQ-AD Depression 2.9 3.1 124 Healthy Japanese volunteers 9929970

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