Reduced 5-HT2A receptor binding in patients with mild cognitive impairment

From Brede Wiki
Jump to: navigation, search
Paper (help)
Reduced 5-HT2A receptor binding in patients with mild cognitive impairment
Authors: Steen G. Hasselbalch, Karine Madsen, Claus Svarer, Lars Hageman Pinborg, Søren Holm, Gunhild Waldemar, Gitte Moos Knudsen
Citation: Neurobiology of Aging 29 (12): 1830-1838. 2008 December
Database(s): PubMed (PMID/17544547)
DOI: 10.1016/j.neurobiolaging.2007.04.011.
Link(s):
Search
Web: Bing Google Yahoo!Google PDF
Article: BASE Google Scholar PubMed
Restricted: DTU Digital Library
Other: NIF
Services
Format: BibTeX Template from PMID
Extract:

Reduced 5-HT2A receptor binding in patients with mild cognitive impairment reports a positron emission tomography study with the fluorine-18 altanserin radioligand on a group of mild cognitive impairment patients and healthy controls.

The study found decrease 5-HT(2A) binding in most neocortical areas.

An abstract of this study was presented at The Sixth International Symposium on Neuroreceptor Mapping.[1]

[edit] Subjects

Subject group #1 (help)
Mild cognitive impairment subjects
Subjects/♂/♀: 16 /  /
Age: 73 (–)
Nationality: define nationality
Approval: define approval
Databases:

Group 1 of 16 mild cognitive impairment subjects were included in the study.

The group had a mean age of 73.
Subject group #2 (help)
Controls
Subjects/♂/♀: 17 /  /
Age: (–)
Nationality: define nationality
Approval: define approval
Databases:

Group 2 of 17 controls were included in the study.


[edit] References

  1. Steen Gregers Hasselbalch, K. Madsen, Claus Svarer, L. Pinborg, J. Stokholm, Søren Holm, Olaf B. Paulson, G. Waldemar, Gitte Moos Knudsen (2006). "5-HT2A receptor binding in mild cognitive impairment: Correlation with cognitive and neuropsychiatric symptoms". NeuroImage 31, supplement 2: T38. doi: 10.1016/j.neuroimage.2006.04.028.
Personal tools