Reduced 5-HT2A receptor binding in patients with mild cognitive impairment
|Reduced 5-HT2A receptor binding in patients with mild cognitive impairment|
|Authors:||Steen G. Hasselbalch, Karine Madsen, Claus Svarer, Lars Hageman Pinborg, Søren Holm, Gunhild Waldemar, Gitte Moos Knudsen|
|Citation:||Neurobiology of Aging 29 (12): 1830-1838. 2008 December|
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|Restricted:||DTU Digital Library|
|Format:||BibTeX Template from PMID|
Reduced 5-HT2A receptor binding in patients with mild cognitive impairment reports a positron emission tomography study with the fluorine-18 altanserin radioligand on a group of mild cognitive impairment patients and healthy controls.
The study found decrease 5-HT(2A) binding in most neocortical areas.
An abstract of this study was presented at The Sixth International Symposium on Neuroreceptor Mapping.
|Subject group #1 (help)|
|Mild cognitive impairment subjects|
|Subjects/♂/♀:||16 / /|
Group 1 of 16 mild cognitive impairment subjects were included in the study.The group had a mean age of 73.
|Subject group #2 (help)|
|Subjects/♂/♀:||17 / /|
Group 2 of 17 controls were included in the study.
- ↑ Steen Gregers Hasselbalch, K. Madsen, Claus Svarer, L. Pinborg, J. Stokholm, Søren Holm, Olaf B. Paulson, G. Waldemar, Gitte Moos Knudsen (2006). "5-HT2A receptor binding in mild cognitive impairment: Correlation with cognitive and neuropsychiatric symptoms". NeuroImage 31, supplement 2: T38. doi: 10.1016/j.neuroimage.2006.04.028.