Right temporoparietal cortex activation during visuo-proprioceptive conflict

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Paper (help)
Right temporoparietal cortex activation during visuo-proprioceptive conflict
Authors: Daniela Balslev, Finn Årup Nielsen, Olaf B. Paulson, Ian Law
Citation: Cerebral Cortex 15 (2): 166–169. 2004
Database(s): BODB Brede Database Google Scholar cites NeuroSynth PubMed (PMID/15238438)
DOI: 10.1093/cercor/bhh119.
Link(s): http://cercor.oxfordjournals.org/cgi/reprint/15/2/166.pdf
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Right temporoparietal cortex activation during visuo-proprioceptive conflict reports a functional magnetic resonance imaging (fMRI) experiment. It was published in 2004 as

Daniela Balslev, Finn Årup Nielsen, Olaf B. Paulson, Ian Law (2004). "Right temporoparietal cortex activation during visuo-proprioceptive conflict". Cerebral Cortex 15(2): 166–169. doi: 10.1093/cercor/bhh119. PMID: 15238438.

The experiment examined the brain response in connection with conflicting information from two senses: visual perception and proprioception. Eleven human research subjects were brain scanned with magnetic resonance imaging while their right index finger was moved on a mouse-like device by one of the experimenters. The position of the finger and the device was displayed to the subject as a cursor on a computer screen, but the motion of the cursor was either in correspondence with the finger motion or it was mirrored. The finger motion should provide the proprioception input to the subject while the cursor display the visual perception. When the finger and the cursor movement are mirrored the subject should experience a visuo-proprioceptive conflict.

Contents

[edit] Subjects

Subject group #1 (help)
Volunteers
Description: Healthy volunteers
Subjects/♂/♀: 11 / 3 / 8
Age: (22–31)
Handedness: right
Nationality: Danish
Approval: Local Ethics Committee
Databases:

Group 1 of 11 right-handed volunteers with 3 males and 8 females were included in the study. The Danish group was from 22 up to 31 years old. The study on the human subjects was approved by the Local Ethics Committee.

[edit] Scanning

MRI Scanning (help)
Mode: fMRI
Scanner: Siemens Vision 1.5T
Type: gradient echoplanar imaging

(TR=4100ms, TE=66ms, FA=90°)

Slices: 24 oriented obliquely between coronal and axial plane
Size: FOV=89mm resolution=3.75x3.75x3.75mm
Laboratory: Danish Research Centre for Magnetic Resonance

For fMRI gradient echoplanar imaging scans were acquired with a 1.5T Siemens Vision at Danish Research Centre for Magnetic Resonance.

MRI Scanning (help)
Mode: aMRI
Scanner: Siemens Vision 1.5T
Type: T1-weighted

(TR=?, TE=?, FA=?)

Slices:
Size: resolution=1x1x1mm
Laboratory: Danish Research Centre for Magnetic Resonance

For aMRI T1-weighted scans were acquired with a 1.5T Siemens Vision at Danish Research Centre for Magnetic Resonance.


[edit] Analysis

After acquisition of the brain scans the researcher processed and analyzed the data within the SPM program. It involved neuroimaging warping for spatial normalization and Gaussian blurring in an attempt to correct for different brain sizes and shapes among the subjects and to be able to report results with reference to a stereotaxic atlas. The final step was statistical analysis with the general linear model and random field theory.

The brain scans with visuo-proprioceptive conflict were statistically compared to the brain scans without. From this comparison the researchers could point to three brain regions which were more active during the conflict, and these areas were reported as 3D points representing peak activity in each region.

[edit] Result

Experiment #1 : Visuoproprioceptive conflict (help)
Description: Movement of a screen cursor in incongruence with passive right index finger movement and detection of transition between conditions with left thumb button press versus movement of the cursor in congruence with the passive finger movement and with button press
Scanning: fMRI BOLD with Siemens Vision at Danish Research Centre for Magnetic Resonance
Topic: Visuoproprioceptive conflict — Brede Database: WOEXT: 417
Analysis: SPM99 — Smoothing: 8mm FWHM
Databases: Brede Database

Anatomy
BA
x
y
z
No. vox
t
z
Coordinate search
Plot
1 Left precentral gyrus/frontal lobe -38 2 37 Brede Database Brede Wiki NeuroSynth SumsDB Not available
2 Right temporoparietal junction 48 -40 9 Brede Database Brede Wiki NeuroSynth SumsDB Not available
3 Right precentral gyrus/frontal lobe Supplementary motor area 51 15 34 Brede Database Brede Wiki NeuroSynth SumsDB Not available

[edit] Discussion

The activation in the right temporoparietal junction is at the border between the temporal lobe and the parietal lobe of the cerebral cortex. An early human brain mapping study with positron emission tomography found that the temporoparietal area was involved in spatial attention,[1] so when vision and proprioception mismatch there may be a conflict in allocating attention to locations in space.

[edit] References

  1. Maurizio Corbetta, F. M. Miezin, Gordon L. Shulman, Steven E. Petersen (1993). "A PET study of visuospatial attention". The Journal of Neuroscience 13(3): 1202–1206. PMID: 8441008.
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