Serotonergic genes and personality traits in the Korean population

From Brede Wiki
Jump to: navigation, search
Paper (help)
Serotonergic genes and personality traits in the Korean population
Authors: Byung-Joo Ham, Yong-Ho Kim, Myung-Jin Choi, Ji-Hyun Cha, Yun-Kyeung Choi, Min-Soo Lee
Citation: Neuroscience Letters 354 (1): 2-5. 2004 January
Database(s): PubMed (PMID/14698468)
DOI: Define doi.
Link(s):
Search
Web: Bing Google Yahoo!Google PDF
Article: BASE Google Scholar PubMed
Restricted: DTU Digital Library
Other: NIF
Services
Format: BibTeX Template from PMID
Extract:

Serotonergic genes and personality traits in the Korean population reports a personality genetics study on the HTR2A A-1438G and HTR6 C267T genetic polymorphisms with personality traits assessed with the Temperament and Character Inventory.

Association analysis is also performed for SLC6A4 5-HTTLPR and TPH1 A218C but no numerical results are reported on statements "We did not find any significant difference for the mean sccores of TCI scales between group L and group S" (p. 3) and "our findings show no significant relationship between TPH A218C polymorphism and TCI score" (p. 4).

[edit] Subjects

Subject group #1 (help)
Korean university staff and students
Subjects/♂/♀: 146 / 47 / 99
Age: 31.94 ±9.05 (–)
Nationality: Korean
Approval: define approval
Databases:

Group 1 of 146 korean university staff and students with 47 males and 99 females were included in the study. The Korean group had a mean age of 31.94.


[edit] Results

Gene Polymorphism Genotype Inventory Trait Mean Std Subjects Recruitment PMID
HTR2A A-1438G A/A TCI Novelty seeking 16.39 5.56 38 Korean university staff and students 14698468
HTR2A A-1438G A/G TCI Novelty seeking 16.75 6.01 84 Korean university staff and students 14698468
HTR2A A-1438G G/G TCI Novelty seeking 16.26 5.63 24 Korean university staff and students 14698468
HTR2A A-1438G A/A TCI Harm avoidance 17.52 6.46 38 Korean university staff and students 14698468
HTR2A A-1438G A/G TCI Harm avoidance 18.21 6.35 84 Korean university staff and students 14698468
HTR2A A-1438G G/G TCI Harm avoidance 15.30 6.41 24 Korean university staff and students 14698468
HTR2A A-1438G A/A TCI Reward dependence 15.35 3.55 38 Korean university staff and students 14698468
HTR2A A-1438G A/G TCI Reward dependence 15.67 3.28 84 Korean university staff and students 14698468
HTR2A A-1438G G/G TCI Reward dependence 15.91 3.26 24 Korean university staff and students 14698468
HTR2A A-1438G A/A TCI Persistence 4.67 1.73 38 Korean university staff and students 14698468
HTR2A A-1438G A/G TCI Persistence 4.47 1.86 84 Korean university staff and students 14698468
HTR2A A-1438G G/G TCI Persistence 5.10 1.82 24 Korean university staff and students 14698468
HTR2A A-1438G A/A TCI Self-directedness 24.14 7.91 38 Korean university staff and students 14698468
HTR2A A-1438G A/G TCI Self-directedness 24.35 7.62 84 Korean university staff and students 14698468
HTR2A A-1438G G/G TCI Self-directedness 28.42 5.39 24 Korean university staff and students 14698468
HTR2A A-1438G A/A TCI Cooperativeness 30.67 5.17 38 Korean university staff and students 14698468
HTR2A A-1438G A/G TCI Cooperativeness 29.36 6.31 84 Korean university staff and students 14698468
HTR2A A-1438G G/G TCI Cooperativeness 29.75 5.82 24 Korean university staff and students 14698468
HTR2A A-1438G A/A TCI Self-transcendence 14.87 6.49 38 Korean university staff and students 14698468
HTR2A A-1438G A/G TCI Self-transcendence 11.99 5.66 84 Korean university staff and students 14698468
HTR2A A-1438G G/G TCI Self-transcendence 14.43 7.66 24 Korean university staff and students 14698468
HTR6 C267T T/T TCI Novelty seeking 15.92 5.43 12 Korean university staff and students 14698468
HTR6 C267T C/T TCI Novelty seeking 17.19 5.76 55 Korean university staff and students 14698468
HTR6 C267T C/C TCI Novelty seeking 16.25 5.91 79 Korean university staff and students 14698468
HTR6 C267T T/T TCI Harm avoidance 17.33 6.27 12 Korean university staff and students 14698468
HTR6 C267T C/T TCI Harm avoidance 16.53 6.89 55 Korean university staff and students 14698468
HTR6 C267T C/C TCI Harm avoidance 18.29 6.09 79 Korean university staff and students 14698468
HTR6 C267T T/T TCI Reward dependence 15.00 3.36 12 Korean university staff and students 14698468
HTR6 C267T C/T TCI Reward dependence 15.62 3.28 55 Korean university staff and students 14698468
HTR6 C267T C/C TCI Reward dependence 15.73 3.39 79 Korean university staff and students 14698468
HTR6 C267T T/T TCI Persistence 5.00 1.86 12 Korean university staff and students 14698468
HTR6 C267T C/T TCI Persistence 4.91 1.59 55 Korean university staff and students 14698468
HTR6 C267T C/C TCI Persistence 4.37 1.94 79 Korean university staff and students 14698468
HTR6 C267T T/T TCI Self-directedness 26.08 6.84 12 Korean university staff and students 14698468
HTR6 C267T C/T TCI Self-directedness 25.22 7.95 55 Korean university staff and students 14698468
HTR6 C267T C/C TCI Self-directedness 24.61 7.34 79 Korean university staff and students 14698468
HTR6 C267T T/T TCI Cooperativeness 29.54 7.71 12 Korean university staff and students 14698468
HTR6 C267T C/T TCI Cooperativeness 29.15 6.46 55 Korean university staff and students 14698468
HTR6 C267T C/C TCI Cooperativeness 30.23 5.28 79 Korean university staff and students 14698468
HTR6 C267T T/T TCI Self-transcendence 17.08 5.73 12 Korean university staff and students 14698468
HTR6 C267T C/T TCI Self-transcendence 13.77 6.46 55 Korean university staff and students 14698468
HTR6 C267T C/C TCI Self-transcendence 12.10 6.12 79 Korean university staff and students 14698468

[edit] Critique

  1. Bias reporting of results: Only scores from genetic polymorphisms with significant associations are reported, thus numerical data is left out for the polymorphisms 5-HTTLPR and A218C.
Personal tools