Serotonin transporter promoter polymorphism, peripheral indexes of serotonin function, and personality measures in families with alcoholism

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Serotonin transporter promoter polymorphism, peripheral indexes of serotonin function, and personality measures in families with alcoholism
Authors: Scott F. Stoltenberg, Geoffrey R. Twitchell, Gregory L. Hanna, Edwin H. Cook, Hiram E. Fitzgerald, Robert A. Zucker, Karley Y. Little
Citation: American journal of medical genetics 114 (2): 230-234. 2002 March
Database(s): PubMed (PMID/11857587)
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Serotonin transporter promoter polymorphism, peripheral indexes of serotonin function, and personality measures in families with alcoholism reports a personality genetics study on the 5-HTTLPR genetic polymorphism.

The study is included in the meta-analysis reported in Meta-analysis of the association between a serotonin transporter promoter polymorphism (5-HTTLPR) and anxiety-related personality traits

[edit] Results

Gene Polymorphism Genotype Inventory Trait Mean Std Subjects Recruitment PMID
SLC6A4 5-HTTLPR long/long NEO-FFI Neuroticism 28.63 8.6 24 American caucasian alcoholics and nonalcoholics 11857587
SLC6A4 5-HTTLPR long/short NEO-FFI Neuroticism 29.20 9.39 45 American caucasian alcoholics and nonalcoholics 11857587
SLC6A4 5-HTTLPR short/short NEO-FFI Neuroticism 27.53 6.76 17 American caucasian alcoholics and nonalcoholics 11857587
SLC6A4 5-HTTLPR long/long NEO-FFI Extraversion 41.04 6.44 24 American caucasian alcoholics and nonalcoholics 11857587
SLC6A4 5-HTTLPR long/short NEO-FFI Extraversion 41.98 6.08 45 American caucasian alcoholics and nonalcoholics 11857587
SLC6A4 5-HTTLPR short/short NEO-FFI Extraversion 42.41 5.47 17 American caucasian alcoholics and nonalcoholics 11857587
SLC6A4 5-HTTLPR long/long NEO-FFI Openness to experience 34.54 5.01 24 American caucasian alcoholics and nonalcoholics 11857587
SLC6A4 5-HTTLPR long/short NEO-FFI Openness to experience 38.29 6.86 45 American caucasian alcoholics and nonalcoholics 11857587
SLC6A4 5-HTTLPR short/short NEO-FFI Openness to experience 38.47 4.53 17 American caucasian alcoholics and nonalcoholics 11857587
SLC6A4 5-HTTLPR long/long NEO-FFI Agreeableness 45.13 4.79 24 American caucasian alcoholics and nonalcoholics 11857587
SLC6A4 5-HTTLPR long/short NEO-FFI Agreeableness 44.71 6.47 45 American caucasian alcoholics and nonalcoholics 11857587
SLC6A4 5-HTTLPR short/short NEO-FFI Agreeableness 46.71 6.88 17 American caucasian alcoholics and nonalcoholics 11857587
SLC6A4 5-HTTLPR long/long NEO-FFI Conscientiousness 46.92 8.14 24 American caucasian alcoholics and nonalcoholics 11857587
SLC6A4 5-HTTLPR long/short NEO-FFI Conscientiousness 44.71 6.47 45 American caucasian alcoholics and nonalcoholics 11857587
SLC6A4 5-HTTLPR short/short NEO-FFI Conscientiousness 48.06 6.27 17 American caucasian alcoholics and nonalcoholics 11857587
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